Ozalevli S, Ozden A, Itil O, Akkoclu A
Dokuz Eylul University, School of Physical Therapy and Rehabilitation, Inciralti, Izmir, Turkey.
Respir Med. 2007 Feb;101(2):286-93. doi: 10.1016/j.rmed.2006.05.007. Epub 2006 Jun 27.
To discuss the utility of Sit-to-Stand Test (STST) compared to the 6min walking test (6MWT) for the evaluation of functional status in patients with chronic obstructive pulmonary disease (COPD).
Fifty-three patients with stable COPD (mean forced expiratory volume in 1s (FEV(1)) 46+/-9% predicted, mean age 71+/-12 year) and 15 healthy individuals (mean FEV(1) 101+/-13% predicted and mean age 63+/-8) were included.
Functional performance was evaluated by STST and 6MWT. During the tests, severity of dyspnea (by Modified Borg Scale), heart rate, pulsed oxygen saturation (SpO(2), by Modified Borg Scale) (by pulse oxymeter), blood pressure were measured. The pulmonary function (by spirometry), quadriceps femoris muscle strength (by manual muscle test) and quality of life (by Nottingham Health Profile Survey) were evaluated.
The STST and 6MWT results were lower in COPD group than the healthy group (P<0.05). During the 6MWT the rise in the heart rate, systolic blood pressure and the decrease in SpO(2) were statistically significant according to STST in COPD groups (P<0.05). The STST and 6MWT were strongly correlated with each other in both groups (P<0.05). Similarly, they were correlated with age, quality of life, peripheral muscle strength and dyspnea severity in COPD groups (P<0.05).
Similar to 6MWT, STST is also able to determine the functional state correctly. Additionally, it produces less hemodynamical stress compared to the 6MWT. In conclusion, STST can be used as an alternative of the 6MWT in patients with COPD.
探讨坐立试验（STST）与6分钟步行试验（6MWT）相比，在评估慢性阻塞性肺疾病（COPD）患者功能状态方面的效用。
纳入53例稳定期COPD患者（1秒用力呼气容积（FEV₁）平均为预计值的46±9%，平均年龄71±12岁）和15名健康个体（FEV₁平均为预计值的101±13%，平均年龄63±8岁）。
通过STST和6MWT评估功能表现。在测试过程中，测量呼吸困难严重程度（采用改良Borg量表）、心率、脉搏血氧饱和度（SpO₂，采用改良Borg量表）（通过脉搏血氧仪）、血压。评估肺功能（通过肺量计）、股四头肌力量（通过徒手肌力测试）和生活质量（通过诺丁汉健康状况调查表）。
COPD组的STST和6MWT结果低于健康组（P<0.05）。在6MWT期间，COPD组中根据STST，心率、收缩压的升高以及SpO₂的降低具有统计学意义（P<0.05）。两组中STST和6MWT彼此高度相关（P<0.05）。同样，在COPD组中它们与年龄、生活质量、外周肌肉力量和呼吸困难严重程度相关（P<0.05）。
与6MWT相似，STST也能够正确地确定功能状态。此外，与6MWT相比，它产生的血流动力学应激较小。总之，STST可作为COPD患者6MWT的替代方法。
