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实验动物疼痛评估与治疗的障碍。

Barriers to assessment and treatment of pain in laboratory animals.

作者信息

Karas Alicia Z

机构信息

Cummings School of Veterinary Medicine at Tufts University, 200 Westboro Rd., North Grafton, MA 01536, USA.

出版信息

Lab Anim (NY). 2006 Jul-Aug;35(7):38-45. doi: 10.1038/laban0706-38.

DOI:10.1038/laban0706-38
PMID:16807565
Abstract

Pain is an undesirable potential consequence of many of the procedures conducted on animals in the course of scientific research, and in most cases it is unnecessary. The US Congress, the public, and laboratory animal medical professionals have indicated that pain should be prevented or minimized in laboratory animals, yet there is ample evidence to suggest that unalleviated pain is still a problem for some laboratory animals. This evidence is circumstantial to some extent but has its basis in problematic issues of pain control in both veterinary and human medicine. The author attempts to identify specific barriers to reduction of pain in laboratory animals. She then seeks to determine the relative importance of each obstacle and to develop approaches to overcoming each obstacle.

摘要

在科学研究过程中,对动物实施的许多操作都可能产生不良的疼痛后果,而且在大多数情况下这种疼痛是不必要的。美国国会、公众以及实验动物医学专业人员都表示,应该在实验动物中预防疼痛或将其降至最低程度,然而,有充分证据表明,未得到缓解的疼痛对一些实验动物来说仍然是个问题。这一证据在一定程度上属于间接证据,但其依据是兽医和人类医学中疼痛控制方面存在的问题。作者试图找出减少实验动物疼痛的具体障碍。然后,她力图确定每个障碍的相对重要性,并制定克服每个障碍的方法。

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Barriers to assessment and treatment of pain in laboratory animals.实验动物疼痛评估与治疗的障碍。
Lab Anim (NY). 2006 Jul-Aug;35(7):38-45. doi: 10.1038/laban0706-38.
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