Schmulson Max, Ortíz Orianna, Santiago-Lomeli Mariana, Gutiérrez-Reyes Gabriela, Gutiérrez-Ruiz María Concepción, Robles-Díaz Guillermo, Morgan Douglas
Liver, Pancreas and Motility Laboratory (HIPAM), Department of Experimental Medicine, Faculty of Medicine, Universidad Nacional Autonoma de Mexico-UNAM, Mexico City, Mexico.
Dig Dis. 2006;24(3-4):342-7. doi: 10.1159/000092887.
The frequency of functional bowel disorders (FBD) in Mexico using the Rome II criteria is unknown.
The Rome II Modular Questionnaire (RII-MQ) was translated into Spanish in coordination with the Rome Committee and their Latin American program. Volunteers were recruited by advertisement in Mexico City, and administered the RII-MQ.
The study population consisted of 324 healthy volunteers, with a mean age of 35.7; 66% were female. The most prevalent disorders were heartburn 35%, irritable bowel syndrome (IBS) 35%, functional bloating 21%, proctalgia fugax 21%, and functional constipation 19%. Based on gender, IBS-C was 4 times more frequent in females than males (19 vs. 4.6%) and functional bloating 3 times more frequent (10 vs. 3.7%). Differences according to occupation included a higher prevalence of ulcer-like dyspepsia (p = 0.04), IBS-C (p = 0.018) and proctalgia fugax (p = 0.034) among students.
This is the first study to use RII-MQ to determine the prevalence of FBD in urban Mexico. The prevalence of IBS was significant and is related to a number of factors, including the stress of living in an overpopulated city. Selection bias is likely operative. A community-based study is warranted.
在墨西哥,采用罗马II标准诊断功能性肠病(FBD)的频率尚不清楚。
与罗马委员会及其拉丁美洲项目协作,将罗马II模块化问卷(RII-MQ)翻译成西班牙语。通过在墨西哥城登广告招募志愿者,并对其进行RII-MQ问卷调查。
研究人群包括324名健康志愿者,平均年龄35.7岁;66%为女性。最常见的疾病为烧心(35%)、肠易激综合征(IBS)(35%)、功能性腹胀(21%)、短暂性直肠疼痛(21%)和功能性便秘(19%)。按性别划分,女性IBS-C的发生率是男性的4倍(19%对4.6%);功能性腹胀是男性的3倍(10%对3.7%)。职业差异方面,学生中溃疡样消化不良(p = 0.04)、IBS-C(p = 0.018)和短暂性直肠疼痛(p = 0.034)的患病率较高。
这是第一项使用RII-MQ来确定墨西哥城市地区FBD患病率的研究。IBS的患病率较高,且与多种因素有关,包括生活在人口过度密集城市的压力。可能存在选择偏倚。有必要开展基于社区的研究。