Schmitt J, Meurer M
Klinik und Poliklinik für Dermatologie am Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden, Fetscherstrasse 74, 01307, Dresden.
Hautarzt. 2006 Aug;57(8):679-84. doi: 10.1007/s00105-006-1193-9.
Most patients with mild to moderate psoriasis require--often longterm--topical treatments: this frequently results in non-compliance especially when large body areas or the face are treated. Monotherapy with anthralin has been abandoned to a great extent while new formulations of topical corticosteroids, vitamin D and vitamin D derivatives have greatly extended the spectrum of topical antipsoriatic treatment modalities. In most instances, combinations of preparations with different pharmacologic modes of action are superior when compared with the respective monotherapy. This also holds true for combinations with a UVB or UVA light therapy. Preparations containing both a corticosteroid and vitamin D derivative are well suited for combining topical treatment with modern systemic antipsoriatic drugs.
大多数轻至中度银屑病患者需要（通常是长期的）局部治疗：这常常导致患者依从性差，尤其是在治疗大面积身体部位或面部时。蒽林单一疗法在很大程度上已被摒弃，而新型局部皮质类固醇、维生素D及维生素D衍生物制剂极大地扩展了局部抗银屑病治疗方式的范围。在大多数情况下，与各自的单一疗法相比，具有不同药理作用方式的制剂联合使用效果更佳。这对于与UVB或UVA光疗联合使用的情况也同样适用。同时含有皮质类固醇和维生素D衍生物的制剂非常适合将局部治疗与现代系统性抗银屑病药物联合使用。
