达托霉素对膜电位依赖性氨基酸转运的抑制作用。
Inhibition of membrane potential-dependent amino acid transport by daptomycin.
作者信息
Allen N E, Alborn W E, Hobbs J N
机构信息
Infectious Disease Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285-0428.
出版信息
Antimicrob Agents Chemother. 1991 Dec;35(12):2639-42. doi: 10.1128/AAC.35.12.2639.
Abstract
Daptomycin inhibits the formation of UDP-N-acetylmuramyl-pentapeptide in Bacillus megaterium by inhibiting active transport of amino acids incorporated into the pentapeptide. The ability of daptomycin to inhibit active transport and peptidoglycan formation may be due to its ability to disrupt the transmembrane electrochemical gradient.
摘要
达托霉素通过抑制掺入五肽中的氨基酸的主动转运，抑制巨大芽孢杆菌中UDP-N-乙酰胞壁酰五肽的形成。达托霉素抑制主动转运和肽聚糖形成的能力可能归因于其破坏跨膜电化学梯度的能力。
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本文引用的文献
1
Uridine diphosphoacetylglucosamine pyrophosphorylase.尿苷二磷酸N-乙酰葡糖胺焦磷酸化酶
J Biol Chem. 1959 Jul;234(7):1822-7.
2
Membrane potential and gentamicin uptake in Staphylococcus aureus.金黄色葡萄球菌的膜电位与庆大霉素摄取
Proc Natl Acad Sci U S A. 1982 Nov;79(21):6693-7. doi: 10.1073/pnas.79.21.6693.
3
Distribution of the phosphoenolpyruvate: glucose phosphotransferase system in bacteria.磷酸烯醇丙酮酸：葡萄糖磷酸转移酶系统在细菌中的分布
J Bacteriol. 1970 Nov;104(2):808-13. doi: 10.1128/jb.104.2.808-813.1970.
4
A simple method for following the fate of alanine-containing components in murein synthesis in Escherichia coli.一种追踪大肠杆菌中胞壁质合成过程中含丙氨酸成分去向的简单方法。
Antonie Van Leeuwenhoek. 1971;37(4):537-52. doi: 10.1007/BF02218524.
5
Control of amino sugar metabolism in Escherichia coli and isolation of mutants unable to degrade amino sugars.大肠杆菌中氨基糖代谢的调控及无法降解氨基糖的突变体的分离
Biochem J. 1968 Feb;106(4):847-58. doi: 10.1042/bj1060847.
6
The mechanism of action of fosfomycin (phosphonomycin).磷霉素的作用机制。
Ann N Y Acad Sci. 1974 May 10;235(0):364-86. doi: 10.1111/j.1749-6632.1974.tb43277.x.
7
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Antimicrob Agents Chemother. 1985 May;27(5):841-5. doi: 10.1128/AAC.27.5.841.
8
In vitro activity and mechanism of action of A21978C1, a novel cyclic lipopeptide antibiotic.新型环脂肽抗生素A21978C1的体外活性及作用机制
Antimicrob Agents Chemother. 1985 Mar;27(3):357-62. doi: 10.1128/AAC.27.3.357.
9
The role of acyl chain character and other determinants on the bilayer activity of A21978C an acidic lipopeptide antibiotic.酰基链特性及其他决定因素对酸性脂肽抗生素A21978C双层活性的作用。
Biochim Biophys Acta. 1986 Jul 24;859(2):219-26. doi: 10.1016/0005-2736(86)90217-8.
10
A21978C, a complex of new acidic peptide antibiotics: isolation, chemistry, and mass spectral structure elucidation.
J Antibiot (Tokyo). 1987 Jun;40(6):761-77. doi: 10.7164/antibiotics.40.761.
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