Springer C, Völcker H E, Rohrschneider K
Augenklinik, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg.
Ophthalmologe. 2006 Sep;103(9):791-7. doi: 10.1007/s00347-006-1396-6.
The purpose of this study was to evaluate and compare retinal function and morphology in patients with central serous chorioretinopathy (CSC) using fundus perimetry and optical coherence tomography (OCT).
In 14 eyes of 14 patients with unilateral and first manifestation of CSC, fundus perimetry with the Microperimeter 1 (MP1) as well as OCT were carried out. The average retinal thickness and the average differential light threshold of the corresponding visual field were analyzed.
All patients presented a serous detachment of the central neurosensory retina with a maximal retinal thickness of 381+/-82 microm. The microperimetric examination revealed on average a mean defect of 8.3+/-3.8 dB, which showed a good correlation to retinal thickness (r=0.73). Likewise, maximal retinal thickness and mean threshold values in the corresponding visual field displayed a good correlation (r=-0.58).
The MP1 enables quantification of functional defects in patients with CSC. Although visual acuity was only slightly reduced, all patients showed extensive scotomata in fundus perimetry, which correlated well with retinal thickness.
本研究旨在使用眼底视野计和光学相干断层扫描（OCT）评估和比较中心性浆液性脉络膜视网膜病变（CSC）患者的视网膜功能和形态。
对14例单侧首发CSC患者的14只眼进行了使用Microperimeter 1（MP1）的眼底视野计检查以及OCT检查。分析了相应视野的平均视网膜厚度和平均微分光阈值。
所有患者均出现中心神经感觉层视网膜浆液性脱离，最大视网膜厚度为381±82微米。微视野检查平均显示平均缺损为8.3±3.8分贝，与视网膜厚度具有良好的相关性（r = 0.73）。同样，相应视野中的最大视网膜厚度和平均阈值也显示出良好的相关性（r = -0.58）。
MP1能够对CSC患者的功能缺陷进行量化。尽管视力仅略有下降，但所有患者在眼底视野计检查中均显示出广泛的暗点，且与视网膜厚度具有良好的相关性。
