Middleton Laura S, Denney Douglas R, Lynch Sharon G, Parmenter Brett
University of Kansas, Department of Psychology, Lawrence, Kansas 66045, USA.
Arch Clin Neuropsychol. 2006 Aug;21(5):487-94. doi: 10.1016/j.acn.2006.06.008. Epub 2006 Aug 1.
The relationship between perceived cognitive functioning and objective cognitive functioning was studied in 221 patients with multiple sclerosis. Perceptions of global cognitive functioning as well as perceptions of performance on specific cognitive tests were assessed. Patients' perceptions of global cognitive functioning in their daily lives were unrelated to their objective performance on the full cognitive test battery. However, patients' perceptions of their performance on specific tasks correlated with their objective performance on those tasks, even though they underestimated their performance on these tasks. The present study also evaluated predictors of patients' perceived cognitive functioning. Depression, anxiety, fatigue, and level of disability predicted perceptions of global cognitive functioning, whereas objective cognitive performance did not. These results add to our understanding of patients' expressed concerns regarding their cognitive functioning in the wake of multiple sclerosis, suggesting that such concerns should be interpreted with caution by clinicians.
对221例多发性硬化症患者的认知功能感知与客观认知功能之间的关系进行了研究。评估了整体认知功能的感知以及特定认知测试中的表现感知。患者在日常生活中对整体认知功能的感知与他们在完整认知测试组合中的客观表现无关。然而，患者对特定任务表现的感知与他们在这些任务上的客观表现相关，尽管他们低估了自己在这些任务上的表现。本研究还评估了患者认知功能感知的预测因素。抑郁、焦虑、疲劳和残疾程度可预测整体认知功能的感知，而客观认知表现则不能。这些结果加深了我们对多发性硬化症患者对其认知功能表达的担忧的理解，表明临床医生在解释这些担忧时应谨慎。
