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Studies on characterization of the integration sites of avian RNA tumor virus-specific DNA.

作者信息

Evans R M, Shoyab M, Baluda M A

出版信息

Cold Spring Harb Symp Quant Biol. 1975;39 Pt 2:1005-7. doi: 10.1101/sqb.1974.039.01.115.

DOI:10.1101/sqb.1974.039.01.115
PMID:169002
Abstract

A sequential hybridization procedure is described which allows the integration sites of viral-specific DNA to be characterized according to their reassociation kinetics. In addition, this approach enables us to estimate the size of the integrated viral DNA. Endogenous virus sequences in normal cells appear to be associated with cell sequences reiterated 1200 times, and each integration unit is approximately equal to one 35S RNA subunit. In AMV-infected cells, the additional AMV-specific DNA sequences reassociate as if they were integrated adjacent to unique cellular DNA or in tandem with the endogenous viral DNA sequences.

摘要

相似文献

1
Studies on characterization of the integration sites of avian RNA tumor virus-specific DNA.
Cold Spring Harb Symp Quant Biol. 1975;39 Pt 2:1005-7. doi: 10.1101/sqb.1974.039.01.115.
2
Differences between the integration of avian myeloblastosis virus DNA in leukemic cells and of endogenous viral DNA in normal chicken cells.禽成髓细胞瘤病毒DNA在白血病细胞中的整合与正常鸡细胞中内源性病毒DNA整合之间的差异。
Proc Natl Acad Sci U S A. 1974 Aug;71(8):3152-6. doi: 10.1073/pnas.71.8.3152.
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Evidence for tandem integration of avian myeloblastosis virus DNA with endogenous provirus in leukemic chicken cells.禽成髓细胞瘤病毒DNA与白血病鸡细胞内源性前病毒串联整合的证据。
Proc Natl Acad Sci U S A. 1976 May;73(5):1749-53. doi: 10.1073/pnas.73.5.1749.
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Quantitative and qualitative differences in DNA complementary to avian myeloblastosis virus between normal and leukemic chicken cells.正常鸡细胞与白血病鸡细胞中与禽成髓细胞瘤病毒互补的DNA的定量和定性差异。
Bibl Haematol. 1975(40):525-36. doi: 10.1159/000397570.
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Acquisition of viral DNA sequences in target organs of chickens infected with avian myeloblastosis virus.感染禽成髓细胞瘤病毒的鸡的靶器官中病毒DNA序列的获取。
J Virol. 1975 Oct;16(4):783-9. doi: 10.1128/JVI.16.4.783-789.1975.
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Ribonucleotide sequence homology among avian oncornaviruses.禽肿瘤病毒之间的核糖核苷酸序列同源性。
J Virol. 1975 Jan;17(1):106-113. doi: 10.1128/JVI.17.1.106-113.1976.
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Homogeneity and complexity of avian oncornavirus proviral DNA determined by molecular hybridization.通过分子杂交测定禽肿瘤病毒前病毒DNA的同质性和复杂性。
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Single-stranded DNA from oncornavirus-infected cells enriched in virus-specific DNA sequences.来自感染肿瘤病毒的细胞的单链DNA富含病毒特异性DNA序列。
Proc Natl Acad Sci U S A. 1977 Sep;74(9):3720-4. doi: 10.1073/pnas.74.9.3720.
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Synthesis of full-length DNA copies of avian myeloblastosis virus RNA in high yields.高产合成禽成髓细胞瘤病毒RNA的全长DNA拷贝。
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10
Restricted addition of proviral DNA in target tissues of chickens infected with avian myeloblastosis virus.禽成髓细胞瘤病毒感染鸡的靶组织中前病毒DNA的限制性添加
Hamatol Bluttransfus. 1976;19:311-25. doi: 10.1007/978-3-642-87524-3_33.

引用本文的文献

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Distribution of bacteriophage phi 3T homologous deoxyribonucleic acid sequences in Bacillus subtilis 168, related bacteriophages, and other Bacillus species.噬菌体phi 3T同源脱氧核糖核酸序列在枯草芽孢杆菌168、相关噬菌体及其他芽孢杆菌属物种中的分布。
J Bacteriol. 1981 Oct;148(1):91-100. doi: 10.1128/jb.148.1.91-100.1981.
2
Integration of proviral DNA in chicken cells infected with Schmidt-Ruppin Rous sarcoma virus is not enhanced by DNA repair.感染施密特 - 鲁平氏劳斯肉瘤病毒的鸡细胞中前病毒DNA的整合不会因DNA修复而增强。
J Virol. 1977 Sep;23(3):533-42. doi: 10.1128/JVI.23.3.533-542.1977.
3
Variations in integration site of avian oncornaviruses in different hosts.
禽肿瘤病毒在不同宿主中整合位点的变异。
J Virol. 1977 Feb;21(2):541-7. doi: 10.1128/JVI.21.2.541-547.1977.
4
Evidence for tandem integration of avian myeloblastosis virus DNA with endogenous provirus in leukemic chicken cells.禽成髓细胞瘤病毒DNA与白血病鸡细胞内源性前病毒串联整合的证据。
Proc Natl Acad Sci U S A. 1976 May;73(5):1749-53. doi: 10.1073/pnas.73.5.1749.