Hou Peiling, Zou Peng, Low Min-Yong, Chan Eli, Koh Hwee-Ling
Department of Pharmacy, Faculty of Science, National University of Singapore, Science Drive 4, Singapore 117543.
Food Addit Contam. 2006 Sep;23(9):870-5. doi: 10.1080/02652030600803856.
An analogue of acetildenafil was detected in an extract of pre-mixed bulk powder. To our knowledge, the powder was destined to be encapsulated and sold as a dietary supplement. The structure was identified by NMR, HR-ESI-MS, ESI-MSn and FTIR analyses. Owing to the inclusion of a hydroxyl group in acetildenafil, the detected compound was called 'hydroxyacetildenafil'. With increasing use of dietary supplements marketed for penile erectile dysfunction, the detection of analogues of sexual performance enhancers is important and timely.
在预混散装粉末提取物中检测到了乙酰西地那非类似物。据我们所知，该粉末拟被封装并作为膳食补充剂出售。通过核磁共振（NMR）、高分辨电喷雾电离质谱（HR-ESI-MS）、电喷雾串联质谱（ESI-MSn）和傅里叶变换红外光谱（FTIR）分析确定了其结构。由于乙酰西地那非中含有一个羟基，因此检测到的化合物被称为“羟基乙酰西地那非”。随着用于阴茎勃起功能障碍的膳食补充剂使用的增加，检测性性能增强剂的类似物既重要又及时。
