Luong Khanh Vinh Quoc, Nguyen Lan Thi Hoang
Vietnamese American Medical Research Foundation, Westminster, California 92683, USA.
Curr Med Chem. 2006;13(20):2443-7. doi: 10.2174/092986706777935050.
Cardiovascular disease (CVD) is the leading cause of death among patients with end-stage renal disease (ESRD). Vitamin D deficiency accompanies the loss of kidney function and is extremely common. Treatment with active vitamin D has improved survival rate in dialysis patients. The relationship between vitamin D and CVD has been reported in the literature. Genetic factors have been known to cause both vitamin D deficiency and CVD. Vitamin D receptor is found in the heart muscle. Vitamin D is reported to be involved in the pathogenesis of many cardiovascular problems. Certainly, vitamin D has an important role in modulating CVD.
心血管疾病（CVD）是终末期肾病（ESRD）患者的主要死因。维生素D缺乏伴随肾功能丧失，极为常见。活性维生素D治疗提高了透析患者的生存率。维生素D与CVD之间的关系已有文献报道。已知遗传因素可导致维生素D缺乏和CVD。在心肌中发现了维生素D受体。据报道，维生素D参与了许多心血管问题的发病机制。当然，维生素D在调节CVD方面具有重要作用。
