Nakagawa Hiroyuki, Takaishi Yoshihisa, Tanaka Naonobu, Tsuchiya Koichiro, Shibata Hirofumi, Higuti Tomihiko
Graduate School of Pharmaceutical Sciences, University of Tokushima, Shomachi, 1-78, Tokushima 770-8505, Japan.
J Nat Prod. 2006 Aug;69(8):1177-9. doi: 10.1021/np060217s.
A methanol extract of the peels of Citrus sudachi gave five new compounds (1-5) and 27 known compounds. The structures were elucidated on the basis of spectroscopic evidence. Several of these compounds were assayed for antimicrobial activity against methicillin-resistant Staphylococcus aureus and Helicobacter pylori, and sudachitin (6) and 3'-demethoxysudachitin (7) were the most active.
酸橘果皮的甲醇提取物得到了5个新化合物(1 - 5)和27个已知化合物。根据光谱数据确定了这些化合物的结构。对其中几种化合物针对耐甲氧西林金黄色葡萄球菌和幽门螺杆菌的抗菌活性进行了测定,酸橘素(6)和3'-去甲氧基酸橘素(7)活性最强。