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硬膜外麻醉下腰椎显微椎间盘切除术:一项对比研究。

Lumbar microdiscectomy under epidural anesthesia: a comparison study.

作者信息

Papadopoulos Elias C, Girardi Federico P, Sama Andrew, Pappou Ioannis P, Urban Michael K, Cammisa Frank P

机构信息

Spine Surgery, Spine Service, Hospital for Special Surgery, New York, NY 10021, USA.

出版信息

Spine J. 2006 Sep-Oct;6(5):561-4. doi: 10.1016/j.spinee.2005.12.002.

Abstract

BACKGROUND CONTEXT

Lumbar microdiscectomy is most commonly performed under general anesthesia, which can be associated with several perioperative morbidities including nausea, vomiting, atelectasis, pulmonary aspiration, and prolonged post-anesthesia recovery. It is possible that fewer complications may occur if the procedure is performed under epidural anesthesia.

PURPOSE

To investigate the safety and efficacy of epidural anesthesia in elective lumbar microdiscectomies.

STUDY DESIGN

A prospective study evaluating the relative morbidities associated with epidural anesthesia and general anesthesia for lumbar microdiscectomy.

PATIENT SAMPLE

Forty-three patients scheduled for primary lumbar microdiscectomy. Two cohorts were formed and were studied separately; one observational of all the 43 patients, and a second cohort of 17 patients who agreed to enter in the randomized trial.

OUTCOME MEASURES

The clinical outcome was determined by the presence of postoperative pain, the absence of anesthesia-related complications, and the overall postoperative recovery.

METHODS

This was a prospective study. With institutional review board approval, 43 consecutive patients were enrolled in the study. However, only 17 patients agreed to be randomized to receive either general or epidural anesthesia for the procedure; the remaining 26 patients selected the type of anesthesia of their preference. Recorded data for all patients included: age; total surgical time; occurrence of nausea, vomiting, atelectasis, or cardiopulmonary complication; ability to arise out of bed on the day of surgery; and the total number of inpatient hospital days. Postoperative pain and satisfaction were assessed only in the randomized cohort.

RESULTS

There were a total of 43 patients, with a mean age of 38.1 years. The patients undergoing epidural anesthesia were marginally older than those undergoing general anesthesia. The epidural and general anesthetic groups were not different with respect to surgical time, pain assessed with a linear visual analogue scale, hospital stay, or the likelihood of arising out of bed on the day of surgery. There were no major cardiopulmonary complications in either group. Patients with epidural anesthesia had significantly less nausea and vomiting.

CONCLUSIONS

Epidural anesthesia as an alternative to general anesthesia has shown less postoperative nausea and vomiting in lumbar microdiscectomy. Nevertheless, given the small number of patients, this study should be considered as preliminary, showing small differences in minor potential complications.

摘要

背景

腰椎间盘显微切除术最常在全身麻醉下进行,这可能会引发多种围手术期并发症,包括恶心、呕吐、肺不张、肺误吸以及麻醉后恢复时间延长。如果该手术在硬膜外麻醉下进行,可能会出现较少的并发症。

目的

探讨硬膜外麻醉在择期腰椎间盘显微切除术中的安全性和有效性。

研究设计

一项前瞻性研究,评估硬膜外麻醉和全身麻醉用于腰椎间盘显微切除术的相关发病率。

患者样本

43例计划进行初次腰椎间盘显微切除术的患者。形成了两个队列并分别进行研究;一个队列观察所有43例患者,另一个队列是17例同意参加随机试验的患者。

观察指标

临床结局通过术后疼痛情况、无麻醉相关并发症以及总体术后恢复情况来确定。

方法

这是一项前瞻性研究。经机构审查委员会批准,连续纳入43例患者。然而,只有17例患者同意随机接受全身麻醉或硬膜外麻醉进行手术;其余26例患者选择了他们偏好的麻醉方式。记录所有患者的数据包括:年龄;总手术时间;恶心、呕吐、肺不张或心肺并发症的发生情况;手术当天起床的能力;以及住院总天数。仅在随机分组队列中评估术后疼痛和满意度。

结果

共有43例患者,平均年龄38.1岁。接受硬膜外麻醉的患者年龄略大于接受全身麻醉的患者。硬膜外麻醉组和全身麻醉组在手术时间、用线性视觉模拟量表评估的疼痛、住院时间或手术当天起床的可能性方面没有差异。两组均未出现重大心肺并发症。接受硬膜外麻醉的患者恶心和呕吐明显较少。

结论

在腰椎间盘显微切除术中,硬膜外麻醉作为全身麻醉的替代方法,术后恶心和呕吐较少。然而,鉴于患者数量较少,本研究应被视为初步研究,显示出在轻微潜在并发症方面的微小差异。

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