Wu Jun Wei, Xing Yu Rong, Wen Yi Bo, Li Tian Fang, Xie Jia Feng, Feng Quan De, Shang Xiao Ping, Li Yun Long, Feng Jin Jin, Wang Xin Xin, Zhai Rong Qun, He Xiang Fei, Chen Tao, Liu Xin Jian, Wen Jian Guo
Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
Int Neurourol J. 2016 Jun;20(2):151-8. doi: 10.5213/inj.1630464.232. Epub 2016 Jun 24.
To investigate the prevalence of spina bifida occulta (SBO) and its relationship with the presence of overactive bladder (OAB) in middle-aged and elderly people in China.
A cross-sectional community-based survey was carried out at 7 communities in Zhengzhou City, China from December 15, 2013 to June 10, 2014, where residents aged over 40 years were randomly selected to participate. All of the participants underwent lumbosacral radiographic analysis and relevant laboratory tests. A questionnaire including basic information, past medical history and present illness, and the OAB symptom score was filled out by all participants. Chi-square tests and logistic regression were used for data analysis with a P-value of <0.05 denoting statistical significance.
A total of 1,061 subjects were qualified for the final statistical analysis (58.8±11.7 years; male, 471 [44.4%]; female, 590 [55.6%]). The overall prevalence of SBO was 15.1% (160 of 1,061): 18.3% (86 of 471) in men and 12.5% (74 of 590) in women. Among these subjects, 13.7% (145 of 1,061) had OAB: 13.2% (62 of 471) in men and 14.1% (83 of 590) in women. The results of logistic regression showed that age, SBO, history of cerebral infarction (HCI), and constipation were risk factors for OAB (P<0.05), while sex, history of childhood enuresis (HCE), body mass index (BMI), and diabetes mellitus (DM) were not (P>0.05). In men, age, SBO, and constipation were risk factors for OAB (P<0.05), while HCE, BMI, DM, HCI, and benign prostate hyperplasia were not (P>0.05). In women, age, SBO, and HCI were risk factors for OAB (P<0.05), while HCE, BMI, DM, vaginal delivery, and constipation were not (P>0.05).
The prevalence of SBO is high and it is related to OAB in middle-aged and elderly people in China.
调查中国中老年人群中隐性脊柱裂（SBO）的患病率及其与膀胱过度活动症（OAB）的关系。
2013年12月15日至2014年6月10日在中国郑州市的7个社区开展了一项基于社区的横断面调查，随机选取40岁以上居民参与。所有参与者均接受腰骶部影像学分析及相关实验室检查。所有参与者填写了一份包括基本信息、既往病史和现病史以及OAB症状评分的问卷。采用卡方检验和逻辑回归进行数据分析，P值<0.05表示具有统计学意义。
共有1061名受试者符合最终统计分析条件（年龄58.8±11.7岁；男性471名[44.4%]；女性590名[55.6%]）。SBO的总体患病率为15.1%（1061例中的160例）：男性为18.3%（471例中的86例），女性为12.5%（590例中的74例）。在这些受试者中，13.7%（1061例中的145例）患有OAB：男性为13.2%（471例中的62例），女性为14.1%（590例中的83例）。逻辑回归结果显示，年龄、SBO、脑梗死病史（HCI）和便秘是OAB的危险因素（P<0.05），而性别、童年遗尿病史（HCE）、体重指数（BMI）和糖尿病（DM）则不是（P>0.05）。在男性中，年龄、SBO和便秘是OAB的危险因素（P<0.05），而HCE、BMI、DM、HCI和良性前列腺增生则不是（P>0.05）。在女性中，年龄、SBO和HCI是OAB的危险因素（P<0.05），而HCE、BMI、DM、阴道分娩和便秘则不是（P>0.05）。
中国中老年人群中SBO的患病率较高，且与OAB有关。
