Young S R, Dyson M
Department of Anatomy, United Medical School, Guy's Hospital, London, England.
Ultrasound Med Biol. 1990;16(3):261-9. doi: 10.1016/0301-5629(90)90005-w.
The effect of therapeutic ultrasound on the formation of new blood vessels in full-thickness excised lesions in the flank skin of adult rats was assessed quantitatively using microfocal x-ray techniques. Wounds were either sham-treated (control group) or exposed to ultrasound for 5 min daily at an intensity of 0.1 W/cm2 SATA (frequency either 0.75 MHz or 3.0 MHz). By 5 days after injury there were more blood vessels in equivalent regions of the granulation tissue of the ultrasound-treated wounds than in the control wounds. This suggested that the ultrasound-treated wounds were at a more advanced stage in the repair process. By 7 days after injury there was no significant difference in blood vessel number between the three groups.
采用微焦点X射线技术定量评估治疗性超声对成年大鼠侧腹皮肤全层切除损伤处新血管形成的影响。伤口要么进行假处理（对照组），要么每天以0.1W/cm² SATA的强度暴露于超声下5分钟（频率为0.75MHz或3.0MHz）。损伤后5天，超声处理伤口的肉芽组织等效区域中的血管比对照伤口更多。这表明超声处理的伤口在修复过程中处于更高级阶段。损伤后7天，三组之间的血管数量没有显著差异。
