Liu W L, Bosman L, Boulos P B, Lau H Y, Pearce F L
Department of Chemistry, University College London, UK.
Agents Actions. 1990 Apr;30(1-2):70-3. doi: 10.1007/BF01969001.
The functional properties of enzymically dispersed mast cells from human lung parenchyma, colonic mucosa and colonic submucosa/muscle were compared. In general, the cells responded in a similar fashion to the histamine releasing action of a variety of immunological and non-immunological stimuli. However, some differences were observed in their responses to anti-allergic compounds. In total, these data indicate that there are subtle variations between human colonic and pulmonary mast cells but that these differences are much less sharply defined than in the rodent.
对来自人肺实质、结肠黏膜和结肠黏膜下层/肌肉的酶分散肥大细胞的功能特性进行了比较。总体而言，这些细胞对多种免疫和非免疫刺激的组胺释放作用的反应方式相似。然而，在它们对抗过敏化合物的反应中观察到了一些差异。总的来说，这些数据表明人结肠肥大细胞和肺肥大细胞之间存在细微差异，但这些差异远不如啮齿动物中的差异那么明显。
