Gallon Frédérique, Marchetti Carole, Jouy Nathalie, Marchetti Philippe
INSERM U814, Faculté de Médecine 1, Lille, France.
Fertil Steril. 2006 Nov;86(5):1526-30. doi: 10.1016/j.fertnstert.2006.03.055. Epub 2006 Sep 25.
By using flow-cytometric sorting, we compared some of the major factors related to fertility in sperm subpopulations with high and low mitochondrial membrane potential (DeltaPsi(m)). Results demonstrate that DeltaPsi(m)(high) spermatozoa represents a subpopulation of sperm with high fertility performance because they have normal morphology, high motility values, and calcium ionophore-induced acrosome reaction, suggesting the importance of mitochondrial functionality for fertilizing capacity of human spermatozoa.
通过流式细胞术分选，我们比较了线粒体膜电位（ΔΨm）高和低的精子亚群中一些与生育能力相关的主要因素。结果表明，ΔΨm（高）精子代表了具有高生育能力的精子亚群，因为它们具有正常的形态、高活力值以及钙离子载体诱导的顶体反应，这表明线粒体功能对于人类精子的受精能力很重要。
