Choi Joanna Mimi, Lew Vincent K, Kimball Alexa B
Harvard Medical School, Boston, Massachusetts, USA.
Pediatr Dermatol. 2006 Sep-Oct;23(5):421-7. doi: 10.1111/j.1525-1470.2006.00276.x.
Despite the common recommendation to wash the face twice daily with a mild cleanser, there is little published evidence to support the practice. Indeed, while the general public believes that cleaner skin will result in fewer blemishes, dermatologists often warn that overwashing and scrubbing can exacerbate the condition. To clarify the effect of frequency of face washing on acne vulgaris, we designed a single-blinded, randomized, controlled clinical trial to be conducted on males with mild to moderate acne vulgaris. Subjects washed their faces twice daily for 2 weeks with a standard mild cleanser before being randomized to one of three study arms, in which face washing was to be done once, twice, or four times a day for 6 weeks. At the end of the study no statistically significant differences were noted between groups. However, significant improvements in both open comedones and total noninflammatory lesions were observed in the group washing twice a day. Worsening of acne condition was observed in the study group washing once a day, with significant increases in erythema, papules, and total inflammatory lesions. We concluded that slight support exists, both in terms of efficacy and convenience, for the recommendation to wash the face twice daily with a mild cleanser. However, excessive face washing may not be as culpable as previously thought.
尽管通常建议每天用温和洁面产品洗脸两次，但几乎没有公开的证据支持这种做法。实际上，虽然普通大众认为皮肤越清洁瑕疵就越少，但皮肤科医生经常警告说过度洗脸和擦洗会使情况恶化。为了阐明洗脸频率对寻常痤疮的影响，我们设计了一项单盲、随机、对照临床试验，将在患有轻度至中度寻常痤疮的男性中进行。受试者先用标准温和洁面产品每天洗脸两次，持续2周，然后被随机分配到三个研究组之一，在接下来的6周里，分别每天洗脸一次、两次或四次。研究结束时，各组之间未发现统计学上的显著差异。然而，每天洗脸两次的组在开放性粉刺和总的非炎性皮损方面均有显著改善。每天洗脸一次的研究组中观察到痤疮情况恶化，红斑、丘疹和总的炎性皮损显著增加。我们得出结论，就疗效和便利性而言，有少许证据支持每天用温和洁面产品洗脸两次的建议。然而，过度洗脸可能并不像之前认为的那样应受指责。
