Sangolkar Lalita N, Maske Sarika S, Chakrabarti Tapan
Environmental Biotechnology Division, National Environmental Engineering Research Institute, Nehru Marg, Nagpur 440 020, India.
Water Res. 2006 Nov;40(19):3485-96. doi: 10.1016/j.watres.2006.08.010. Epub 2006 Oct 2.
Episodes of cyanobacterial toxic blooms and fatalities to animals and humans due to cyanobacterial toxins (CBT) are known worldwide. The hepatotoxins and neurotoxins (cyanotoxins) produced by bloom-forming cyanobacteria have been the cause of human and animal health hazards and even death. Prevailing concentration of cell bound endotoxin, exotoxin and the toxin variants depend on developmental stages of the bloom and the cyanobacterial (CB) species involved. Toxic and non-toxic strains do not show any predictable morphological difference. The current instrumental, immunological and molecular methods applied for determining microcystins (peptide hepatotoxins) and microcystin-producing cyanobacteria are reviewed.
蓝藻毒性水华事件以及蓝藻毒素（CBT）导致动物和人类死亡的情况在全球都为人所知。形成水华的蓝藻产生的肝毒素和神经毒素（蓝藻毒素）一直是人类和动物健康危害甚至死亡的原因。细胞结合内毒素、外毒素和毒素变体的普遍浓度取决于水华的发育阶段以及所涉及的蓝藻（CB）物种。有毒和无毒菌株没有表现出任何可预测的形态差异。本文综述了目前用于测定微囊藻毒素（肽肝毒素）和产生微囊藻毒素的蓝藻的仪器、免疫和分子方法。
