Poultney Christopher S, Gutiérrez Rodrigo A, Katari Manpreet S, Gifford Miriam L, Paley W Bradford, Coruzzi Gloria M, Shasha Dennis E
Courant Institute of Mathematical Sciences, New York University, New York, NY, USA.
Bioinformatics. 2007 Jan 15;23(2):259-61. doi: 10.1093/bioinformatics/btl496. Epub 2006 Oct 2.
Sungear is a software system that supports a rapid, visually interactive and biologist-driven comparison of large datasets. The datasets can come from microarray experiments (e.g. genes induced in each experiment), from comparative genomics (e.g. genes present in each genome) or even from non-biological applications (e.g. demographics or baseball statistics). Sungear represents multiple datasets as vertices in a polygon. Each possible intersection among the sets is represented as a circle inside the polygon. The position of the circle is determined by the position of the vertices represented in the intersection and the area of the circle is determined by the number of elements in the intersection. Sungear shows which Gene Ontology terms are over-represented in a subset of circles or anchors. The intuitive Sungear interface has enabled biologists to determine quickly which dataset or groups of datasets play a role in a biological function of interest.
A live online version of Sungear can be found at http://virtualplant-prod.bio.nyu.edu/cgi-bin/sungear/index.cgi
Sungear是一个软件系统，支持对大型数据集进行快速、可视化交互且由生物学家驱动的比较。这些数据集可以来自微阵列实验（例如每个实验中诱导的基因）、比较基因组学（例如每个基因组中存在的基因），甚至来自非生物学应用（例如人口统计学或棒球统计数据）。Sungear将多个数据集表示为多边形中的顶点。集合之间的每个可能交集都表示为多边形内的一个圆。圆的位置由交集中表示的顶点位置决定，圆的面积由交集中的元素数量决定。Sungear显示哪些基因本体术语在一组圆或锚点中过度代表。直观的Sungear界面使生物学家能够快速确定哪些数据集或数据集组在感兴趣的生物学功能中起作用。
可在http://virtualplant-prod.bio.nyu.edu/cgi-bin/sungear/index.cgi找到Sungear的在线实时版本。
