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鼻内镜切除鼻窦内翻性乳头状瘤后的长期生活质量:一家三级学术医院的6年队列分析

Long-term quality of life after endoscopic removal of sinonasal inverted papillomas: a 6-year cohort analysis in a tertiary academic hospital.

作者信息

van Samkar Anusha, Georgalas Christos

机构信息

Department of ENT and Skull Base Center, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

Department of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

Eur Arch Otorhinolaryngol. 2016 Jun;273(6):1433-7. doi: 10.1007/s00405-015-3751-1. Epub 2015 Aug 18.

Abstract

Inverted papillomas may affect the (para)nasal cavity. While some of these papillomas can undergo malignant transformation, others grow slowly and cause few if any symptoms. An endoscopic approach is seen as providing a balance between the greatest removal possible and avoiding unnecessary morbidity. However, the actual long-term quality of life of patients having undergone surgery for inverted papillomas has never been studied. Our primary aim is to assess the long-term sequelae and the quality of life of patients after endoscopic surgery of sinonasal inverted papillomas. The secondary aim is to establish which nasal symptoms, if any, are the most prevalent before and after surgery. We used the SNOT-22 questionnaire to assess the quality of life of patients who had undergone endoscopic surgery for sinonasal inverted papillomas between 2000 and 2011. Twenty-seven out of 34 patients returned the questionnaire (79 % response rate). Median follow-up was 6 years (range 1-10). Mean age was 58.9 years (range 40-85). Median SNOT-22 score was 12, while the most frequent postoperative symptom was the need to blow the nose (18 patients) and the most frequent preoperative symptom was nasal obstruction. Patients after endoscopic removal of sinonasal inverted papillomas return to an almost normal quality of life, as measured by the disease-specific questionnaire SNOT-22. The most frequent symptom was the need to blow the nose.

摘要

内翻性乳头状瘤可累及(副)鼻腔。虽然其中一些乳头状瘤可发生恶变,但其他的生长缓慢,很少甚至没有症状。内镜手术被认为在尽可能彻底切除肿瘤与避免不必要的并发症之间取得了平衡。然而,接受内翻性乳头状瘤手术患者的实际长期生活质量从未得到研究。我们的主要目的是评估鼻窦内翻性乳头状瘤内镜手术后患者的长期后遗症和生活质量。次要目的是确定手术前后最常见的鼻部症状(如有)。我们使用SNOT - 22问卷评估了2000年至2011年间接受鼻窦内翻性乳头状瘤内镜手术患者的生活质量。34名患者中有27名返回了问卷(回复率79%)。中位随访时间为6年(范围1 - 10年)。平均年龄为58.9岁(范围40 - 85岁)。SNOT - 22评分中位数为12分,术后最常见的症状是需要擤鼻(18例患者),术前最常见的症状是鼻塞。通过疾病特异性问卷SNOT - 22评估,鼻窦内翻性乳头状瘤内镜切除术后患者的生活质量几乎恢复正常。最常见的症状是需要擤鼻。

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