Nürnberger Thorsten, Kemmerling Birgit
Department of Plant Biochemistry, Center for Plant Molecular Biology, Eberhard-Karls-University Tübingen, Auf der Morgenstelle 5, D-72076 Tübingen, Germany.
Trends Plant Sci. 2006 Nov;11(11):519-22. doi: 10.1016/j.tplants.2006.09.005. Epub 2006 Oct 9.
Plant innate immunity is activated either upon perception of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs) or upon resistance (R) protein-mediated recognition of pathogen race-specific effector molecules. Although many plant R proteins have been identified, there is only limited knowledge about plant PRRs. Recently, Cyril Zipfel et al. identified a second Arabidopsis leucine-rich repeat receptor protein kinase implicated in PAMP perception, which suggests that several members of this large protein family function as pattern recognition receptors.
植物先天免疫可通过模式识别受体(PRR)识别病原体相关分子模式(PAMP)或通过抗性(R)蛋白介导识别病原体小种特异性效应分子来激活。尽管已鉴定出许多植物R蛋白,但对植物PRR的了解仍然有限。最近,西里尔·齐普费尔等人鉴定出了第二种参与PAMP识别的拟南芥富含亮氨酸重复序列受体蛋白激酶,这表明这个大蛋白家族的几个成员作为模式识别受体发挥作用。