复发性继发性阴茎肿瘤
Secondary penile tumours revisited.
作者信息
Cherian Jacob, Rajan Sreekumar, Thwaini Ali, Elmasry Yaser, Shah Tariq, Puri Rajiv
机构信息
Department of urology, Bradford teaching hospitals, Bradford, UK.
出版信息
Int Semin Surg Oncol. 2006 Oct 11;3:33. doi: 10.1186/1477-7800-3-33.
OBJECTIVE
To highlight the salient features of metastatic malignancies involving the penis, with special reference to the primary tumour sites, metastatic mechanisms, clinical features, differential diagnosis, treatment and prognosis.
METHODS
A comprehensive search of the literature was performed using MEDLINE and EMBASE, using the keywords 'penis', 'secondary malignancy', 'metastasis' and 'malignant priapism' to identify reviews and case reports of secondary penile malignancy. A case of rare clinical presentation of metastatic penile lesion is presented along with the review of the literature.
CONCLUSION
Secondary malignancy of the penis is a rare clinical entity, despite the rich vascularisation of this organ. The majority of metastatic lesions take their origin from the neighbouring genito-urinary organs, mainly prostate and bladder. These lesions are often associated with disseminated malignancy and hence have a poor outcome. Nodular or ulcerative lesions involving the corpora cavernosa or priapism are the main modes of clinical presentation. In most cases, only palliative or supportive therapy is indicated.
目的
强调累及阴茎的转移性恶性肿瘤的显著特征，特别提及原发肿瘤部位、转移机制、临床特征、鉴别诊断、治疗及预后。
方法
使用MEDLINE和EMBASE对文献进行全面检索，以“阴茎”“继发性恶性肿瘤”“转移”和“恶性阴茎异常勃起”为关键词，识别继发性阴茎恶性肿瘤的综述和病例报告。本文报告了一例转移性阴茎病变罕见临床表现的病例，并对文献进行了综述。
结论
尽管阴茎血管丰富，但阴茎继发性恶性肿瘤是一种罕见的临床实体。大多数转移性病变起源于邻近的泌尿生殖器官，主要是前列腺和膀胱。这些病变常与播散性恶性肿瘤相关，因此预后较差。累及海绵体的结节性或溃疡性病变或阴茎异常勃起是主要的临床表现形式。在大多数情况下，仅需进行姑息或支持治疗。
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