长期使用阿司匹林与结直肠癌风险：瑞典的一项队列研究。
Long-term aspirin use and colorectal cancer risk: a cohort study in Sweden.
作者信息
Larsson S C, Giovannucci E, Wolk A
机构信息
Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
出版信息
Br J Cancer. 2006 Nov 6;95(9):1277-9. doi: 10.1038/sj.bjc.6603442. Epub 2006 Oct 24.
Abstract
In a prospective cohort study of 74 250 Swedish women and men, with 7.2 years of follow-up and 705 incident colorectal cancer cases, long duration of aspirin use (>20 years) was associated with a reduced risk of colorectal cancer (multivariate rate ratio: 0.65; 95% confidence interval: 0.45-0.94). Aspirin use for a shorter period was not associated with risk.
摘要
在一项针对74250名瑞典男性和女性的前瞻性队列研究中，随访7.2年，共出现705例结直肠癌病例，长期服用阿司匹林（>20年）与结直肠癌风险降低相关（多变量率比：0.65；95%置信区间：0.45 - 0.94）。较短时间服用阿司匹林与风险无关。
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本文引用的文献
1
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2
Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer.
JAMA. 2005 Aug 24;294(8):914-23. doi: 10.1001/jama.294.8.914.
3
Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial.
JAMA. 2005 Jul 6;294(1):47-55. doi: 10.1001/jama.294.1.47.
4
Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial.
Gastroenterology. 2003 Aug;125(2):328-36. doi: 10.1016/s0016-5085(03)00887-4.
5
A randomized trial of aspirin to prevent colorectal adenomas.
N Engl J Med. 2003 Mar 6;348(10):891-9. doi: 10.1056/NEJMoa021735.
6
A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer.
N Engl J Med. 2003 Mar 6;348(10):883-90. doi: 10.1056/NEJMoa021633.
7
Aspirin and cancer risk: an update to 2001.
Eur J Cancer Prev. 2002 Dec;11(6):535-42. doi: 10.1097/00008469-200212000-00005.
8
Low-dose aspirin and incidence of colorectal tumors in a randomized trial.
J Natl Cancer Inst. 1993 Aug 4;85(15):1220-4. doi: 10.1093/jnci/85.15.1220.
9
Completeness of the Swedish Cancer Register. Non-notified cancer cases recorded on death certificates in 1978.
Acta Radiol Oncol. 1984;23(5):305-13. doi: 10.3109/02841868409136026.
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