Fiorentini A, Valente R, Perciaccante A, Tubani L
Int J Cardiol. 2007 Jan 8;114(2):E50-2. doi: 10.1016/j.ijcard.2006.07.213. Epub 2006 Oct 30.
Sleep is one of the most important factors contributing to health. Although same studies examining the relationship between sleep duration and mortality, has not been fully discussed. We consecutively studied two hundred and fifty Caucasian subjects, normoweight, who were referred for ambulatory blood pressure monitoring (APM). Quality of sleep was evaluated through the Pittsburgh Sleep Quality Index (PSQI). PSQI assessed subjective sleep quality of the past 4 weeks and was administered during the personal interview. A global PSQI > or =5 has a diagnostic sensitivity of 89.6 and specificity of 86.5 in distinguishing "poor sleepers"(PSQI > or =5) from "good sleepers" (PSQI <5) subjects. Hypertension, type 2 diabetes mellitus and sleep's quality disorders were reported respectively in 53.4%, 12.5% and 35.2% of the total population examined. The prevalence of hypertension was 87.1% in "poor sleepers" subjects versus 35.1% in "good sleepers" subjects (p<0.0001). Our results permit to conclude that, as the sleep-disordered breathing, also the sleep's quality disorders, evaluated by PSQI, are associated with significant comorbidities, as hypertension and diabetes mellitus. We hypothesize that the valuation of the quality of sleep through the Pittsburgh Sleep Quality Index (PSQI) could be considered in screening for cardiovascular risk.
睡眠是促进健康的最重要因素之一。尽管一些研究探讨了睡眠时间与死亡率之间的关系，但尚未得到充分讨论。我们连续研究了250名体重正常的白种人受试者，他们被转诊进行动态血压监测（APM）。通过匹兹堡睡眠质量指数（PSQI）评估睡眠质量。PSQI评估过去4周的主观睡眠质量，并在个人访谈期间进行。在区分“睡眠质量差者”（PSQI≥5）和“睡眠质量好者”（PSQI＜5）时，PSQI总分≥5的诊断敏感性为89.6，特异性为86.5。在接受检查的总人口中，高血压、2型糖尿病和睡眠质量障碍的报告率分别为53.4%、12.5%和35.2%。“睡眠质量差者”中高血压患病率为87.1%，而“睡眠质量好者”中为35.1%（p＜0.0001）。我们的结果表明，与睡眠呼吸紊乱一样，通过PSQI评估的睡眠质量障碍也与高血压和糖尿病等重大合并症相关。我们假设，通过匹兹堡睡眠质量指数（PSQI）评估睡眠质量可用于心血管风险筛查。
