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从可食用褐藻树状艾氏藻中分离出一种新的抗过敏间苯三酚鞣质，即间苯二酚岩藻呋喃二酚-B。

Isolation of a new anti-allergic phlorotannin, phlorofucofuroeckol-B, from an edible brown alga, Eisenia arborea.

作者信息

Sugiura Yoshimasa, Matsuda Kohji, Yamada Yasuhiro, Nishikawa Masashi, Shioya Kazufumi, Katsuzaki Hirotaka, Imai Kunio, Amano Hideomi

机构信息

Department of Technology, Kanehatsu Food Co., Ltd. Yutaka, Minami-ku, Nagoya, Aichi, Japan.

出版信息

Biosci Biotechnol Biochem. 2006 Nov;70(11):2807-11. doi: 10.1271/bbb.60417. Epub 2006 Nov 7.

DOI:10.1271/bbb.60417
PMID:17090915
Abstract

Eisenia arborea is an edible brown alga occasionally used as a folk medicine in gynecopathy in Japan. A new phlorotannin was isolated from the alga during our search for naturally occurring anti-allergic compounds from edible algae guided by the inhibitory effect on histamine release from rat basophile leukemia (RBL)-2H3 cells. The phlorotannin was called "phlorofucofuroeckol-B." Its structure was determined by spectral analysis and chemical conversion. This paper describes the isolation, structure elucidation, and inhibitory effect of phlorofucofuroeckol-B on histamine release.

摘要

树状艾氏藻是一种可食用的褐藻，在日本偶尔被用作妇科的民间药物。在我们以对大鼠嗜碱性白血病（RBL）-2H3细胞组胺释放的抑制作用为指导，从可食用藻类中寻找天然抗过敏化合物的过程中，从该藻类中分离出了一种新的间苯三酚鞣质。这种间苯三酚鞣质被称为“间苯三酚岩藻呋喃醚醇-B”。其结构通过光谱分析和化学转化确定。本文描述了间苯三酚岩藻呋喃醚醇-B的分离、结构解析及其对组胺释放的抑制作用。

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