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[药物治疗在毛发结构性病变和弥漫性脱发中的疗效——比较双盲研究]

[The efficacy of drug therapy in structural lesions of the hair and in diffuse effluvium--comparative double blind study].

作者信息

Petri H, Pierchalla P, Tronnier H

机构信息

Hautklinik der Städt. Kliniken Dortmund Akademisches Lehrkrankenhaus, Universitäts-Hautklinik Witten-Herdecke.

出版信息

Schweiz Rundsch Med Prax. 1990 Nov 20;79(47):1457-62.

PMID:1709511
Abstract

Growth and quality of hair was studied after treatment with Pantogar, another prescription (Verum-2) and placebo for four months in 60 patients with diffuse effluvium capillorum and agnogenic structural alternations of hair. Efficacy was assessed by measurements of swelling, dye-binding and thickness for hair-quality and evaluation of hair-density and trichograms for hair-growth. Statistical analysis of swelling properties and trichogram data indicated that Pantogar was effective, the second preparation improved quality of hair and retarded hair loss. Placebo was ineffective judged by the used parameters. Tolerance of the treatment was good and adverse effects could not be substantiated.

摘要

在60例患有弥漫性脱发及特发性毛发结构改变的患者中,研究了泛多加利、另一种处方药(真品-2)和安慰剂治疗四个月后的毛发生长及发质情况。通过测量头发的膨胀度、染料结合力和厚度来评估发质,通过评估头发密度和毛发图谱来评估毛发生长。对膨胀特性和毛发图谱数据的统计分析表明,泛多加利有效,第二种制剂改善了发质并延缓了脱发。根据所使用的参数判断,安慰剂无效。治疗耐受性良好,未证实有不良反应。

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