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胃肠胰内分泌激素对N-甲基-N'-硝基-N-亚硝基胍诱导的大鼠胃癌组织发生的影响；特别提及硬癌性胃癌的发展

Effect of gastro-entero-pancreatic endocrine hormones on the histogenesis of gastric cancer in rats induced by N-methyl-N'-nitro-N-nitrosoguanidine; with special reference to development of scirrhous gastric cancer.

作者信息

Tahara E, Haizuka S

出版信息

Gan. 1975 Aug;66(4):421-6.

PMID:171195
Abstract

One of five gastro-entero-pancreatic hormones, gastrin, serotonin, histamine, glucagon, and insulin, was intraperitoneally administered for a long period to the rats that received N-methy-N'-nitro-N-nitrosoguanidine. A frequent development of scirrhous carcinoma was demonstrated in the group treated with gastrin.

摘要

将胃泌素、血清素、组胺、胰高血糖素和胰岛素这五种胃肠胰激素之一长期腹腔注射给接受N-甲基-N'-硝基-N-亚硝基胍的大鼠。结果表明，在接受胃泌素治疗的组中，硬癌的发生率很高。

相似文献

1
Effect of gastro-entero-pancreatic endocrine hormones on the histogenesis of gastric cancer in rats induced by N-methyl-N'-nitro-N-nitrosoguanidine; with special reference to development of scirrhous gastric cancer.胃肠胰内分泌激素对N-甲基-N'-硝基-N-亚硝基胍诱导的大鼠胃癌组织发生的影响；特别提及硬癌性胃癌的发展
Gan. 1975 Aug;66(4):421-6.
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Effect of fundic ulcers induced by iodoacetamide on development of gastric tumors in rats treated with N-methyl-N'-nitro-N-nitrosoguanidine.碘乙酰胺诱导的胃底溃疡对用N-甲基-N'-硝基-N-亚硝基胍处理的大鼠胃肿瘤发生的影响。
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Enhanced effect of gastrin on rat stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine.胃泌素对N-甲基-N'-硝基-N-亚硝基胍诱导的大鼠胃癌发生的增强作用。
Cancer Res. 1982 May;42(5):1781-7.
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Effect of prolonged administration of gastrin on experimental carcinogenesis in rat stomach induced by N-methyl-N' -nitro-N-nitrosoguanidine.
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Immunofluorescent staining of gastric mucosal glycoprotein in gastric carcinoma of dogs and rats induced by N-methyl-N'-nitro-N-nitrosoguanidine.
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Effect of plastic bead on gastric carcinogenesis in rats treated with N-methyl-N'-nitro-N-nitrosoguanidine.
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[The effect of vagotomy on carcinogenesis in the glandular stomach of rats, induced by N-methyl-N'-nitro-N-nitrosoguanidine].
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Effect of gastrin on gastric mucosal cyclic adenosine 3':5'-monophosphate-dependent protein kinase activity in rat stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine.胃泌素对N-甲基-N'-硝基-N-亚硝基胍诱导的大鼠胃癌发生过程中胃黏膜环磷腺苷依赖性蛋白激酶活性的影响。
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引用本文的文献

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Inhibition of gastric tumorigenesis by alpha-difluoromethylornithine in rats treated with N-methyl-N'-nitro-N-nitrosoguanidine.α-二氟甲基鸟氨酸对用N-甲基-N'-硝基-N-亚硝基胍处理的大鼠胃肿瘤发生的抑制作用。
J Cancer Res Clin Oncol. 1993;119(10):594-8. doi: 10.1007/BF01372722.
2
Induction of glandular stomach cancers in C3H mice treated with N-methyl-N-nitrosourea in the drinking water.用饮用水中的N-甲基-N-亚硝基脲处理C3H小鼠诱发腺胃癌。
Jpn J Cancer Res. 1993 Dec;84(12):1258-64. doi: 10.1111/j.1349-7006.1993.tb02831.x.
3
Effects of hypochlorhydria and hypergastrinemia on structure and function of gastrointestinal cells. A review and analysis.
胃酸过少和高胃泌素血症对胃肠道细胞结构和功能的影响。综述与分析。
Dig Dis Sci. 1995 Feb;40(2 Suppl):50S-62S. doi: 10.1007/BF02214871.
4
Induction of carcinoids in the glandular stomach of rats by N-methyl-N'-nitro-N-nitrosoguanidine.N-甲基-N'-硝基-N-亚硝基胍诱导大鼠腺胃类癌的发生。
J Cancer Res Clin Oncol. 1981;100(1):1-12. doi: 10.1007/BF00405896.
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The effect of antioxidants on MNNG-induced stomach carcinogenesis in rats.抗氧化剂对大鼠中N-甲基-N'-硝基-N-亚硝基胍诱导的胃癌发生的影响。
J Cancer Res Clin Oncol. 1986;112(3):272-5. doi: 10.1007/BF00395922.
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Achlorhydria: hypergastrinaemia: carcinoids--a flawed hypothesis?胃酸缺乏：高胃泌素血症：类癌——一个有缺陷的假说？
Gut. 1987 Apr;28(4):488-505. doi: 10.1136/gut.28.4.488.
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Polyamine levels and gastrin receptors in colon cancers.结肠癌中的多胺水平与胃泌素受体
Ann Surg. 1988 Jun;207(6):662-9. doi: 10.1097/00000658-198806000-00004.
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Gastrin receptors in human gastric scirrhous carcinoma.人胃硬癌中的胃泌素受体
Gastroenterol Jpn. 1988 Aug;23(4):384-9. doi: 10.1007/BF02779205.
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Therapeutic achlorhydria and risk of gastric cancer.治疗性胃酸缺乏与胃癌风险
Gastroenterol Jpn. 1989 Oct;24(5):585-96. doi: 10.1007/BF02773894.
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Induction of signet ring cell carcinomas in X-irradiated hypocatalasemic mice (C3H/Cbs).在经X射线照射的低过氧化氢酶血症小鼠（C3H/Cbs）中诱导印戒细胞癌。
Jpn J Cancer Res. 1991 Nov;82(11):1175-7. doi: 10.1111/j.1349-7006.1991.tb01774.x.