Anthony P P, James P D
J Clin Pathol. 1975 Aug;28(8):647-55. doi: 10.1136/jcp.28.8.647.
Three cases of adenoid cystic carcinoma have been identified in a 10-year review of 2686 cases of breast carcinoma. The criteria necessary for diagnosis have been reviewed with particular reference to cribriform intraduct carcinoma and adenocarcinoma of the breast with small, dark, 'basaloid'-cell pattern. The most important single diagnostic criterion of adenoid cystic carcinoma is a biphasic cellular pattern which may be aded by the demonstration of two types of mucin stromal acid mucopolysaccharide and ductal neutral mucopolysaccharide. This tumour most frequently presents as a painful or tender mass near the areola, and it carries a uniquely favourable prognosis when compared with similar tumours elsewhere in the body. Actomyosin has been demonstrated in all three tumours by an immunofluorescent method, and this supports a predominantly myoepithelial origin.
在对2686例乳腺癌病例进行的10年回顾中，发现了3例腺样囊性癌。已对诊断所需的标准进行了回顾，特别参考了筛状导管内癌和具有小而暗的“基底样”细胞模式的乳腺腺癌。腺样囊性癌最重要的单一诊断标准是双相细胞模式，这可以通过两种类型的粘蛋白（基质酸性粘多糖和导管中性粘多糖）的证明来补充。这种肿瘤最常表现为乳晕附近的疼痛性或压痛性肿块，与身体其他部位的类似肿瘤相比，其预后特别良好。通过免疫荧光法在所有3例肿瘤中均检测到肌动球蛋白，这支持其主要起源于肌上皮。
