Briers P J, Hoorweg J, Stanfield J P
Acta Paediatr Scand. 1975 Nov;64(6):853-8. doi: 10.1111/j.1651-2227.1975.tb03936.x.
Three groups of Ugandan children, 18 in each group, and one comparison group of 18 children were examined at 11-17 years of age. The three groups had previously been admitted for treatment of protein energy malnutrition between the ages of 8 to 15, 16 to 21 and 22 to 27 months respectively. The comparison group had not been clinically malnourished throughout the period up to 27 months of age. The children came from one tribe and from similar socio-economic background, and were individually matched on age and sex. The bone age was estimated by hand wrist radiography scored for maturity by the Tanner & Whitehouse method. The metacarpal index, a ratio derived from the medullary width and full diameter of the mid-point of the second metacarpal, was used as a measure of bone cortical thickness. The three malnourished groups are significantly shorter in height than the comparison group, but are not different in bone age and metacarpal index. No differences are observed between the three groups of children who had been admitted for protein energy malnutrition at different ages. The findings are discussed as they relate to the existing literature.
对三组乌干达儿童（每组18名）以及一组由18名儿童组成的对照组进行了检查，这些儿童年龄在11至17岁之间。这三组儿童此前分别在8至15个月、16至21个月和22至27个月时因蛋白质能量营养不良入院接受治疗。对照组在27个月龄之前的整个期间均未出现临床营养不良情况。这些儿童来自同一个部落，社会经济背景相似，并且在年龄和性别上进行了个体匹配。通过手腕X线摄影采用坦纳和怀特豪斯方法对成熟度评分来估计骨龄。掌骨指数是由第二掌骨中点的髓腔宽度与全长直径得出的比值，用作骨皮质厚度的衡量指标。这三组营养不良的儿童身高明显低于对照组，但骨龄和掌骨指数并无差异。在不同年龄因蛋白质能量营养不良入院的三组儿童之间未观察到差异。结合现有文献对研究结果进行了讨论。
