Toepke Michael W, Beebe David J
Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
Lab Chip. 2006 Dec;6(12):1484-6. doi: 10.1039/b612140c. Epub 2006 Oct 4.
Microfluidic devices made out of polydimethylsiloxane (PDMS) have many physical properties that are useful for cell culture applications, such as transparency and gas permeability. Another distinct characteristic of PDMS is its ability to absorb hydrophobic small molecules. Partitioning of molecules into PDMS can significantly change solution concentrations and could potentially alter experimental outcomes. Herein we discuss PDMS absorption and its potential impact on microfluidic experiments.
由聚二甲基硅氧烷（PDMS）制成的微流控装置具有许多对细胞培养应用有用的物理特性，如透明度和透气性。PDMS的另一个显著特性是其吸收疏水性小分子的能力。分子在PDMS中的分配会显著改变溶液浓度，并可能改变实验结果。在此，我们讨论PDMS吸收及其对微流控实验的潜在影响。
