Henry Alasdair L, Kyle Simon D, Bhandari Sahil, Chisholm Anna, Griffiths Christopher E M, Bundy Christine
Centre for Dermatology Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.
Manchester Centre for Health Psychology, University of Manchester, Manchester, United Kingdom.
PLoS One. 2016 Jun 21;11(6):e0157843. doi: 10.1371/journal.pone.0157843. eCollection 2016.
Psoriasis is a long-term immune-mediated inflammatory disorder mainly, but not only, affecting skin, and is associated with significant medical and psychological morbidity. Evidence suggests that sleep is disrupted in psoriasis, however high quality empirical evidence is lacking. Given the importance of sleep for health, characterisation of sleep disruption in psoriasis is an important goal. We therefore conducted a systematic review of the sleep-psoriasis literature.
Searches were conducted in Pubmed, SCOPUS and Web of Science from inception to May 2016. Studies were compared against inclusion/exclusion criteria and underwent a quality evaluation. Given the heterogeneity of studies, we conducted a narrative synthesis of the findings.
Searches revealed 32 studies which met our predetermined inclusion/exclusion criteria. Whilst 93.7% of studies reported sleep disruption in this population, ranging from 0.05% to 85.4%, many had important methodological shortcomings. Over half of all quantitative studies (54.8%; 17/31) relied on non-validated measures, contributing to heterogeneity in study findings. In those that employed valid measures, assessing sleep was often not the primary objective. We frequently found the absence of adequate sample size calculations and poor statistical reporting.
This review showed that in psoriasis, reported sleep rates of sleep disturbance varied substantially. Most studies lacked a hypothesis driven research question and/or failed to use validated measures of sleep. We were unable to draw firm conclusions about the precise prevalence and nature of sleep disturbance within the psoriasis population. We offer suggestions to help advance understanding of sleep disturbance in psoriasis.
银屑病是一种长期的免疫介导的炎症性疾病，主要但不限于影响皮肤，并与严重的医学和心理疾病相关。有证据表明银屑病患者存在睡眠障碍，但高质量的实证证据不足。鉴于睡眠对健康的重要性，明确银屑病患者的睡眠障碍特征是一个重要目标。因此，我们对银屑病与睡眠相关的文献进行了系统综述。
在PubMed、SCOPUS和Web of Science数据库中进行检索，检索时间跨度从建库至2016年5月。将检索到的研究与纳入/排除标准进行对比，并进行质量评估。鉴于研究的异质性，我们对研究结果进行了叙述性综合分析。
检索共发现32项研究符合我们预先设定的纳入/排除标准。虽然93.7%的研究报告了该人群存在睡眠障碍，比例从0.
