半导体量子棒作为单分子荧光生物标记物。
Semiconductor quantum rods as single molecule fluorescent biological labels.
作者信息
Fu Aihua, Gu Weiwei, Boussert Benjamin, Koski Kristie, Gerion Daniele, Manna Liberato, Le Gros Mark, Larabell Carolyn A, Alivisatos A Paul
机构信息
Department of Chemistry, University of California Berkeley, and Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
出版信息
Nano Lett. 2007 Jan;7(1):179-82. doi: 10.1021/nl0626434.
Abstract
In this paper, we report the development of rod-shaped semiconductor nanocrystals (quantum rods) as fluorescent biological labels. Water-soluble biocompatible quantum rods have been prepared by surface silanization and applied for nonspecific cell tracking as well as specific cellular targeting. Quantum rods are brighter single molecule probes as compared to quantum dots. They have many potential applications as biological labels in situations where their properties offer advantages over quantum dots.
摘要
在本文中，我们报告了棒状半导体纳米晶体（量子棒）作为荧光生物标记物的发展情况。通过表面硅烷化制备了水溶性生物相容性量子棒，并将其应用于非特异性细胞追踪以及特异性细胞靶向。与量子点相比，量子棒是更亮的单分子探针。在其特性优于量子点的情况下，它们作为生物标记物有许多潜在应用。
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