Kulshrestha Shatavari, Khan Asad U
Dr. D. Y. Patil Biotechnology & Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, India.
Medical Microbiology and Molecular Biology, Laboratory Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, India.
IET Nanobiotechnol. 2018 Dec;12(8):1009-1017. doi: 10.1049/iet-nbt.2018.5112.
Nanoparticle-based treatment has become a potential therapeutic approach. The nanosize of these particles provides them with unique physicochemical properties and enhances their interaction with the biological system. Nanomaterials have the potential to overcome some of the major issues in the clinical world which may include cancer treatment and may be utilised to resolve the major problem of drug resistance in infection control. These particles are being used to improve present therapeutics by virtue of their shape, size and diverse intrinsic as well as chemical properties. The authors have discussed the use of nanoparticles in cancer treatment, infections caused by multidrug-resistant microbial strains and biofilm inhibition along with the detailed description of the current status of nanomaterials in the field of medicine.
基于纳米颗粒的治疗已成为一种潜在的治疗方法。这些颗粒的纳米尺寸赋予它们独特的物理化学性质，并增强了它们与生物系统的相互作用。纳米材料有潜力克服临床领域的一些主要问题，其中可能包括癌症治疗，并且可用于解决感染控制中耐药性这一主要问题。这些颗粒因其形状、大小以及多样的固有和化学性质而被用于改进现有治疗方法。作者们讨论了纳米颗粒在癌症治疗、多重耐药微生物菌株引起的感染以及生物膜抑制方面的应用，同时详细描述了纳米材料在医学领域的现状。
