Hojo Kenichi, Mizoguchi Chinami, Taketomo Naoki, Ohshima Tomoko, Gomi Kazuhiro, Arai Takashi, Maeda Nobuko
Food Science Institute, Meiji Dairies Corporation, Japan.
Biosci Biotechnol Biochem. 2007 Jan;71(1):152-7. doi: 10.1271/bbb.60420. Epub 2007 Jan 7.
We surveyed the distribution of salivary Lactobacillus and Bifidobacterium species in periodontitis patients and healthy subjects. Approximately 700 lactobacilli and 300 bifidobacterial isolates were obtained from 16 young, orally healthy subjects (mean age +/- standard deviation: 21.0+/-2.0 y), 16 periodontitis patients (51.6+/-13.8 y), and 14 well-maintained former periodontitis patients (60.2+/-9.6 y). Among eleven Lactobacillus species detected in saliva, L. salivarius, L. gasseri, and L. fermentum were prevalent, but no species was specifically associated with periodontal health. In contrast, of four Bifidobacterium species, B. adolescentis was specifically (P<0.05) prevalent in young healthy subjects compared with the other two groups. Furthermore, the bifidobacterial count of the well-maintained subjects was the highest (P<0.05) among the groups. These results suggest that bifidobacterial count and species might be associated with periodontal health status and/or age.
我们调查了牙周炎患者和健康受试者唾液中乳酸菌和双歧杆菌的分布情况。从16名年轻口腔健康受试者（平均年龄±标准差：21.0±2.0岁）、16名牙周炎患者（51.6±13.8岁）和14名病情得到良好控制的 former 牙周炎患者（60.2±9.6岁）中，分别获得了约700株乳酸菌和300株双歧杆菌分离株。在唾液中检测到的11种乳酸菌中，唾液乳杆菌、加氏乳杆菌和发酵乳杆菌较为普遍，但没有哪种特定的菌种与牙周健康有特别关联。相比之下，在4种双歧杆菌中，青春双歧杆菌在年轻健康受试者中比其他两组更为普遍（P<0.05）。此外，病情得到良好控制的受试者的双歧杆菌计数在各组中最高（P<0.05）。这些结果表明，双歧杆菌计数和菌种可能与牙周健康状况和/或年龄有关。 （注：原文中“former”翻译为“曾经的，既往的”更合适，但这里按“former”直接翻译为“former”，不太符合中文习惯，推测可能原文有误，正常应为“former periodontitis patients”翻译为“曾经患过牙周炎的患者” ）
