牛分枝杆菌（卡介苗菌株）和免疫梅毒血清预处理对家兔抵抗梅毒螺旋体能力的影响。
Effect of pretreatment with Mycobacterium bovis (strain BCG) and immune syphilitic serum on rabbit resistance to Treponema pallidum.
作者信息
Graves S R, Johnson R C
出版信息
Infect Immun. 1975 Nov;12(5):1029-36. doi: 10.1128/iai.12.5.1029-1036.1975.
Abstract
Stimulation of the rabbit reticuloendothelial system with viable Mycobacterium bovis (strain BCG), and other agents, had no effect on the development of syphilitic lesions after intradermal or intravenous inoculation with graded doses of Treponema pallidum (virulent Nichol's strain; mean infective doses less than 10). The simultaneous administration of immune syphilitic rabbit serum retarded the development of lesions, but this appeared to be due solely to the immune serum, suggesting no synergism between the activated reticuloendothelial system and the anti-T. pallidum antibodies. The administration of two doses of BCG enhanced syphilitic lesion development in the rabbit.
摘要
用活的牛分枝杆菌（卡介苗菌株）及其他制剂刺激兔网状内皮系统，对皮内或静脉接种不同剂量梅毒螺旋体（强毒尼科尔菌株；平均感染剂量小于10）后梅毒损害的发展没有影响。同时给予免疫梅毒兔血清可延缓损害的发展，但这似乎完全是由于免疫血清所致，提示活化的网状内皮系统与抗梅毒螺旋体抗体之间不存在协同作用。给予两剂卡介苗可促进兔梅毒损害的发展。
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Effect of pretreatment with Mycobacterium bovis (strain BCG) and immune syphilitic serum on rabbit resistance to Treponema pallidum.牛分枝杆菌（卡介苗菌株）和免疫梅毒血清预处理对家兔抵抗梅毒螺旋体能力的影响。
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