正常兔、经牛型结核分枝杆菌卡介苗处理的兔以及免疫梅毒兔血液中梅毒螺旋体强毒株（Nichols株）的清除率
Rate of clearance of virulent Treponema pallidum (Nichols) from the blood stream of normal, Mycobacterium bovis BCG-treated, and immune syphilitic rabbits.
作者信息
Graves S
出版信息
Infect Immun. 1980 Jan;27(1):264-7. doi: 10.1128/iai.27.1.264-267.1980.
Abstract
The rate of clearance of virulent Treponema pallidum (Nichols) from the blood stream of normal rabbits and rabbits previously treated with Mycobacterium bovis BCG was similar, there being treponemes still circulating 8 h after intravenous inoculation. In contrast, immune syphilitic rabbits cleared the virulent treponemes within 1 to 2 hours. Rabbits with passive humoral immunity to T. pallidum (after the transfer of 70 ml of immune serum) showed a similar clearance rate to that of the immune rabbits. Rabbits previously treated with BCG and with passive humoral immunity did not show a synergistic enhanced clearance rate, it being similar to that of immune rabbits.
摘要
从正常兔和先前用牛型结核分枝杆菌卡介苗治疗过的兔的血流中清除毒力梅毒螺旋体（Nichols株）的速率相似，静脉接种8小时后仍有螺旋体在循环。相比之下，免疫性梅毒兔在1至2小时内清除了毒力螺旋体。对梅毒螺旋体具有被动体液免疫的兔（在输注70毫升免疫血清后）显示出与免疫兔相似的清除率。先前用卡介苗治疗并具有被动体液免疫的兔没有表现出协同增强的清除率，其与免疫兔的清除率相似。
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