Harris Jennifer R, Magnus Per, Tambs Kristian
Department of Genes and Environment, Division of Epidemiology, The Norwegian Institute of Public Health, Nydalen, N-0403 Oslo, Norway.
Twin Res Hum Genet. 2006 Dec;9(6):858-64. doi: 10.1375/183242706779462886.
The population-based twin program of research at the Norwegian Institute of Public Health (NIPH) was begun in 1992. It consists of a number of questionnaire and clinical interview projects exploring a broad array of mental and physical health outcomes. This article provides a brief update summarizing our research activities, some research highlights, new developments and potentials for further developing the program of twin research. In the most recent years a large effort has concentrated on completing a mental health interview study of Axis I psychiatric and substance use disorders and Axis II personality disorders. Although still in the early planning phases, one of the most significant developments is that an agreement is now in place to centralize the Norwegian twin data into a national Norwegian Twin Registry. This new registry will include twin cohorts born from 1905 onwards. Other resources for building twin projects are described. Nationally, there is great potential for linking the NIPH twin data with other health registries and with information in a number of Norway's large population-based biobank studies. Internationally, platforms such as those developed within GenomEUtwin, for data standards and data sharing and access are greatly facilitating international collaborations in twin research.
挪威公共卫生研究所(NIPH)基于人群的双胞胎研究项目始于1992年。它包括一些问卷调查和临床访谈项目,探讨了广泛的身心健康结果。本文简要介绍了我们的研究活动、一些研究亮点、新进展以及双胞胎研究项目进一步发展的潜力。近年来,大量工作集中在完成一项关于轴I精神障碍和物质使用障碍以及轴II人格障碍的心理健康访谈研究。尽管仍处于早期规划阶段,但最重大的进展之一是现在已达成一项协议,将挪威双胞胎数据集中到一个国家挪威双胞胎登记处。这个新的登记处将包括1905年以后出生的双胞胎队列。还介绍了开展双胞胎项目的其他资源。在国内,将NIPH双胞胎数据与其他健康登记处以及挪威一些大型基于人群的生物银行研究中的信息相联系具有很大潜力。在国际上,诸如GenomEUtwin内部开发的用于数据标准、数据共享和访问的平台极大地促进了双胞胎研究的国际合作。