Chuang W C, Cheng C M, Chang H C, Chen Y P, Sheu S J
Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan, Republic of China.
Planta Med. 1999 Aug;65(6):567-71. doi: 10.1055/s-1999-14028.
A total of 33 commercial samples of Evodiae fructus originated from the rutaceous plants Evodia rutaecarpa (Juss.) Benth. and E. rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang (= E. officinalis Dode), respectively, were collected from Taiwan's herbal market. The contents of eighteen constituents (including 15 alkaloids, 2 flavonoids and 1 diterpenoid) in these samples were determined by high-performance liquid chromatography within 60 minutes. Analysis results showed that the constituent contents were almost unrelated to the species, but rather closely related to the degrees of maturity of the fruit. Those fruits with open mouths and unsplit ovaries had the highest total contents, fruits with open mouths and split ovaries had lower contents, and fruits with closed mouths had the lowest contents. In terms of the individual constituents, the open-mouth fruits contained higher contents of dehydroevodiamine, evodiamine, evocarpine and rutaecarpine, whereas the closed-mouth fruits had higher contents of dehydroevodiamine, epimedoside C, evocarpine and evodiamine.
总共从台湾草药市场收集了33个吴茱萸商业样品，它们分别来源于芸香科植物吴茱萸（Evodia rutaecarpa (Juss.) Benth.）和吴茱萸变种（Evodia rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang (= Evodia officinalis Dode)）。通过高效液相色谱法在60分钟内测定了这些样品中18种成分（包括15种生物碱、2种黄酮类化合物和1种二萜类化合物）的含量。分析结果表明，成分含量几乎与物种无关，而是与果实的成熟度密切相关。那些开口且子房未裂开的果实总含量最高，开口且子房裂开的果实含量较低，而闭口的果实含量最低。就单个成分而言，开口果实中脱氢吴茱萸碱、吴茱萸碱、吴茱萸次碱和吴茱萸新碱的含量较高，而闭口果实中脱氢吴茱萸碱、朝藿定C、吴茱萸次碱和吴茱萸碱的含量较高。
