You Tae-Min, Choi Byung-Ho, Li Jingxu, Jung Jae-Hyung, Lee Hyeon-Jung, Lee Seoung-Ho, Jeong Seung-Mi
Department of Oral & Maxillofacial Surgery, College of Dentistry, Yonsei University, Seoul, South Korea.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Apr;103(4):e8-12. doi: 10.1016/j.tripleo.2006.11.042. Epub 2007 Jan 31.
The aim of this study was to examine the influence of platelet-rich plasma (PRP) used as an adjunct to Bio-Oss for the repair of bone defects adjacent to titanium dental implants.
In 6 mongrel dogs, 12 screw-shaped titanium dental implants were inserted into the osteotomy sites in the dogs' tibias. Before implantation, a standardized gap (2.0 mm) was created between the implant surface and the surrounding bony walls. The gaps were filled with either Bio-Oss cancellous granules alone or Bio-Oss cancellous granules mixed with PRP.
After 4 months, the Bio-Oss-treated defects revealed a significantly higher percentage of bone-implant contact than the defects treated with Bio-Oss and PRP (60.1% vs. 30.8%; P < .05).
The results indicate that when PRP is used as an adjunct to Bio-Oss in the repair of bone defects adjacent to titanium dental implants, PRP may decrease periimplant bone healing.
本研究旨在探讨富血小板血浆（PRP）作为Bio-Oss辅助材料用于修复钛牙种植体周围骨缺损的影响。
在6只杂种犬中，将12枚螺旋形钛牙种植体植入犬胫骨的截骨部位。植入前，在种植体表面与周围骨壁之间制造一个标准化间隙（2.0毫米）。间隙分别用单独的Bio-Oss松质颗粒或与PRP混合的Bio-Oss松质颗粒填充。
4个月后，Bio-Oss治疗的缺损显示骨-种植体接触百分比显著高于Bio-Oss和PRP治疗的缺损（60.1%对30.8%；P <.05）。
结果表明，当PRP作为Bio-Oss辅助材料用于修复钛牙种植体周围骨缺损时，PRP可能会降低种植体周围骨愈合。
