Young Joel L, Redmond Judith C
Rochester Center for Behavioral Medicine, Rochester Hills, MI.
Psychopharmacol Bull. 2007;40(1):118-26.
Adult attention deficit hyperactivity disorder (ADHD) may share common features with fibromyalgia syndrome (FMS) and chronic fatigue syndrome (CFS). In an outpatient psychiatric clinic, a number of adult patients who presented primarily with symptoms of ADHD, predominately inattentive type, also reported unexplained fatigue, widespread musculoskeletal pain or a pre-existing diagnosis of CFS or FMS. As expected, ADHD pharmacotherapy usually attenuated the core ADHD symptoms of inattention, distractibility, hyperactivity, and impulsivity. Less expected was the observation that some patients also reported amelioration of pain and fatigue symptoms. The utility of ADHD medications in FMS and CFS states may be their innate arousal and enhanced filtering properties. This model supposes that FMS and CFS are central processing problems rather than peripheral disorders of muscles and joints.
成人注意力缺陷多动障碍(ADHD)可能与纤维肌痛综合征(FMS)和慢性疲劳综合征(CFS)有共同特征。在一家门诊精神科诊所,许多主要表现为ADHD症状(主要是注意力不集中型)的成年患者也报告了不明原因的疲劳、广泛的肌肉骨骼疼痛,或先前已确诊的CFS或FMS。正如预期的那样,ADHD药物治疗通常会减轻注意力不集中、易分心、多动和冲动等核心ADHD症状。不太预期的是观察到一些患者还报告疼痛和疲劳症状有所改善。ADHD药物在FMS和CFS状态中的效用可能在于其固有的唤醒和增强的过滤特性。该模型假设FMS和CFS是中枢处理问题,而非肌肉和关节的外周疾病。