自闭症和/或注意力缺陷多动障碍女性的慢性疼痛与健康相关生活质量：一项前瞻性纵向研究。
Chronic Pain And Health-Related Quality Of Life In Women With Autism And/Or ADHD: A Prospective Longitudinal Study.
作者信息
Asztély Karin, Kopp Svenny, Gillberg Christopher, Waern Margda, Bergman Stefan
机构信息
Department of Public Health and Community Medicine, Sahlgrenska Academy Institute of Medicine, Göteborg, Sweden.
Gillberg Neuropsychiatric Centre, Sahlgrenska Academy Institute of Neuroscience and Physiology, Göteborg, Sweden.
出版信息
J Pain Res. 2019 Oct 18;12:2925-2932. doi: 10.2147/JPR.S212422. eCollection 2019.
PURPOSE
To investigate the prevalence of chronic pain and its association with health-related quality of life (HRQoL) in a group of women, diagnosed with autism spectrum disorder (ASD) and/or attention deficit hyperactive disorder (ADHD) in childhood.
PATIENTS AND METHODS
Prospective longitudinal 16-19 years follow-up study of 100 Swedish females diagnosed with ASD and/or ADHD in childhood/adolescence. Seventy-seven of the women were included in the current sub-study, using validated measures of pain perception and quality of life.
RESULTS
A large majority of the women (76.6%) reported chronic pain. HRQoL was low overall and lower still for those reporting chronic pain. Women with ADHD who had ongoing treatment with stimulants reported a significant lower prevalence of chronic widespread pain (CWP) than those not treated.
CONCLUSION
Comorbidity with chronic pain is common in women with ASD and/or ADHD and important to address in the clinic since it is associated with an already low HRQoL. Treatment for ADHD might reduce the pain in some cases.
目的
调查一组童年时期被诊断患有自闭症谱系障碍（ASD）和/或注意力缺陷多动障碍（ADHD）的女性中慢性疼痛的患病率及其与健康相关生活质量（HRQoL）的关联。
患者与方法
对100名在童年/青少年时期被诊断患有ASD和/或ADHD的瑞典女性进行为期16 - 19年的前瞻性纵向随访研究。使用经过验证的疼痛感知和生活质量测量方法，77名女性被纳入当前的子研究。
结果
绝大多数女性（76.6%）报告有慢性疼痛。总体而言，HRQoL较低，而报告有慢性疼痛的女性HRQoL更低。正在接受兴奋剂治疗的ADHD女性报告的慢性广泛性疼痛（CWP）患病率显著低于未接受治疗的女性。
结论
ASD和/或ADHD女性中慢性疼痛合并症很常见，在临床中很重要，因为它与本就较低的HRQoL相关。ADHD的治疗在某些情况下可能会减轻疼痛。
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