Ahmed Atallah F, Tai Shu-Hui, Wu Yang-Chang, Sheu Jyh-Horng
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Steroids. 2007 Apr;72(4):368-74. doi: 10.1016/j.steroids.2007.01.001. Epub 2007 Jan 16.
Four new trihydroxysteroids, sinugrandisterols A-D (1-4), have been isolated from the CH(2)Cl(2)-soluble fraction of the EtOH extract of Sinularia grandilobata. The structures of these metabolites were determined on the basis of spectroscopic (IR, MS, and 1D and 2D NMR) analysis. The cytotoxicity of 1-4 toward a limited panel of cancer cell lines is also reported.
从大花软珊瑚（Sinularia grandilobata）乙醇提取物的二氯甲烷可溶部分中分离出了四种新的三羟基甾体化合物，即中华软珊瑚甾醇A-D（1-4）。通过光谱分析（红外光谱、质谱以及一维和二维核磁共振）确定了这些代谢产物的结构。还报道了1-4对一组有限的癌细胞系的细胞毒性。
