Cai Steven, Cannizzo Francis, Bullard Dunn Kelli M, Gibbs John F, Czuczman Myron, Rajput Ashwani
Department of Surgery, The State University of New York at Buffalo, Buffalo, NY, USA.
Am J Surg. 2007 Mar;193(3):409-12; discussion 412. doi: 10.1016/j.amjsurg.2006.12.007.
Gastrointestinal involvement of non-Hodgkin's lymphoma (NHL), although rare, may require surgical intervention. The purpose of the current study was to determine the incidence, presentation, and management of patients with NHL of the colon or rectum.
Demographic data, signs, symptoms, disease stage, and treatment of patients with a primary gastrointestinal lymphoma treated between 1973 and 2005 were identified.
Forty-three of 244 gastrointestinal lymphoma patients (18%) had colon or rectal involvement. Most common symptoms on presentation were pain (49%), hematochezia (49%), change in bowel habits (23%), and weight loss (19%). Most common site of involvement was the ileocecum. Twenty-six patients (60%) required surgery. The majority (56%) had urgent or emergent operations.
Colorectal involvement by NHL occurred in 18% of patients with gastrointestinal lymphoma. Surgery was required for pain, obstruction, and/or bleeding. Physicians caring for patients must be aware of the potential need for surgery in treating this patient population.
非霍奇金淋巴瘤（NHL）累及胃肠道虽罕见，但可能需要手术干预。本研究旨在确定结肠或直肠NHL患者的发病率、临床表现及治疗方法。
确定1973年至2005年间接受治疗的原发性胃肠道淋巴瘤患者的人口统计学数据、体征、症状、疾病分期及治疗情况。
244例胃肠道淋巴瘤患者中有43例（18%）累及结肠或直肠。最常见的临床表现为疼痛（49%）、便血（49%）、排便习惯改变（23%）及体重减轻（19%）。最常累及的部位是回盲部。26例患者（60%）需要手术治疗。大多数患者（56%）接受了急诊或紧急手术。
18%的胃肠道淋巴瘤患者出现结直肠受累。因疼痛、梗阻和/或出血需要进行手术。治疗此类患者的医生必须意识到在治疗该人群时可能需要手术。
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