爱沙尼亚塔林注射吸毒者中血源病毒感染的高流行率及高危行为
High prevalence of blood-borne virus infections and high-risk behaviour among injecting drug users in Tallinn, Estonia.
作者信息
Uusküla Anneli, McNutt Louise Anne, Dehovitz Jack, Fischer Krista, Heimer Robert
机构信息
Department of Public Health, University of Tartu, Estonia.
出版信息
Int J STD AIDS. 2007 Jan;18(1):41-6. doi: 10.1258/095646207779949907.
Abstract
The HIV epidemic in Estonia is rapidly expanding, and injection drug users (IDUs) are the major risk group contributing to the expansion. A convenience sample of 159 IDUs visiting syringe-exchange programmes (SEPs) was selected to quantify the association of HIV-risk behaviours and blood-borne infections. A high prevalence of HIV, hepatitis B core antibody (HBVcore), hepatitis B surface antigen (HbsAg) and hepatitis C virus antibodies (56, 85.1, 21.3, and 96.2%, respectively) was associated with high-risk injections, unsafe sexual behaviour and alcohol abuse. These findings emphasize the importance of evidence-based secondary prevention among the HIV-infected, especially given the uncertain sustainability of antiretroviral and substance abuse treatments.
摘要
爱沙尼亚的艾滋病疫情正在迅速蔓延，注射吸毒者是导致疫情蔓延的主要风险群体。我们选取了159名前往针头交换项目（SEP）的注射吸毒者作为便利样本，以量化艾滋病风险行为与血源感染之间的关联。艾滋病病毒、乙肝核心抗体（HBVcore）、乙肝表面抗原（HbsAg）和丙肝病毒抗体的高流行率（分别为56%、85.1%、21.3%和96.2%）与高风险注射、不安全的性行为及酗酒有关。这些发现强调了对艾滋病感染者进行循证二级预防的重要性，尤其是考虑到抗逆转录病毒治疗和药物滥用治疗的可持续性尚不确定。
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