Receptor tyrosine kinase-G-protein coupled receptor complex signaling in mammalian cells.
作者信息
Pyne Nigel J, Waters Catherine M, Long Jaclyn S, Moughal Noreen A, Tigyi Gabor, Pyne Susan
机构信息
Department of Physiology and Pharmacology, Strathclyde Institute for Biomedical Sciences, University of Strathclyde, 27 Taylor St, Glasgow G4 0NR, UK.
出版信息
Adv Enzyme Regul. 2007;47:271-80. doi: 10.1016/j.advenzreg.2006.12.011. Epub 2007 Mar 6.
Abstract
摘要
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Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells.鞘氨醇激酶1是MCF-7人乳腺癌细胞迁移、增殖和存活所必需的。
FEBS Lett. 2005 Oct 10;579(24):5313-7. doi: 10.1016/j.febslet.2005.08.055.
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Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells.胰岛素样生长因子-1受体（IGF-1R）在人MDA-MB-231乳腺癌上皮细胞中对CXCR4的反式激活作用。
J Biol Chem. 2005 Dec 2;280(48):39701-8. doi: 10.1074/jbc.M509829200. Epub 2005 Sep 19.
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LPA-induced epithelial ovarian cancer (EOC) in vitro invasion and migration are mediated by VEGF receptor-2 (VEGF-R2).溶血磷脂酸（LPA）诱导的上皮性卵巢癌（EOC）体外侵袭和迁移由血管内皮生长因子受体-2（VEGF-R2）介导。
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c-Src is involved in regulating signal transmission from PDGFbeta receptor-GPCR(s) complexes in mammalian cells.c-Src参与调控哺乳动物细胞中血小板衍生生长因子β受体-G蛋白偶联受体复合物的信号传导。
Cell Signal. 2005 Feb;17(2):263-77. doi: 10.1016/j.cellsig.2004.07.011.
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