使用快速乳胶凝集试验Pyloriset诊断成人和儿童患者的幽门螺杆菌感染
Diagnosis of Helicobacter pylori infection in adult and pediatric patients by using Pyloriset, a rapid latex agglutination test.
作者信息
Westblom T U, Madan E, Gudipati S, Midkiff B R, Czinn S J
机构信息
Department of Medicine, St. Louis University School of Medicine, Missouri 63104.
出版信息
J Clin Microbiol. 1992 Jan;30(1):96-8. doi: 10.1128/jcm.30.1.96-98.1992.
Pyloriset (Orion Diagnostica, Espoo, Finland) is a rapid antibody test using latex particles coated with acid-extracted antigen of Helicobacter pylori. We evaluated its ability to predict infection in 100 adult patients and 50 pediatric patients referred for gastric endoscopy. Sixty of 65 H. pylori-infected adults were correctly identified by the test. There were 12 false-positive and 5 false-negative reactions seen. Pyloriset had a sensitivity of 92% and a specificity of 66%. The positive predictive value was 83% and the negative predictive value 82%. In contrast, sensitivity dropped to 36% in the pediatric patients and the positive predictive value was only 40%. Pyloriset could become an important alternative to other more time-consuming diagnostic tests for H. pylori-infected adult patients but is inadequate for diagnosis of pediatric H. pylori infection.
Pyloriset（芬兰埃斯波的奥立安诊断公司）是一种快速抗体检测方法，使用涂有幽门螺杆菌酸提取抗原的乳胶颗粒。我们评估了它在100名成年患者和50名因胃内镜检查前来就诊的儿科患者中预测感染的能力。该检测正确识别出了65名幽门螺杆菌感染成年患者中的60名。出现了12例假阳性和5例假阴性反应。Pyloriset的敏感性为92%，特异性为66%。阳性预测值为83%，阴性预测值为82%。相比之下，儿科患者的敏感性降至36%，阳性预测值仅为40%。对于幽门螺杆菌感染的成年患者，Pyloriset可能成为其他耗时更长的诊断检测的重要替代方法，但不足以用于诊断儿科幽门螺杆菌感染。
Zotero 插件