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自膨式金属支架治疗恶性结肠梗阻:瑞典的经验

Self-expanding metal stents in malignant colonic obstruction: experiences from Sweden.

作者信息

Lepsenyi Mattias, Santen Stefan, Syk Ingvar, Nielsen Jörgen, Nemeth Artur, Toth Ervin, Thorlacius Henrik

机构信息

Department of Surgery, Skane University Hospital Malmö, Lund University, S-20502 Malmö, Sweden.

出版信息

BMC Res Notes. 2011 Jul 30;4:274. doi: 10.1186/1756-0500-4-274.

Abstract

BACKGROUND

Acute surgery in the management of malignant colonic obstruction is associated with high morbidity and mortality. The use of self-expanding metal stents (SEMS) is an alternative method of decompressing colonic obstruction. SEMS may allow time to optimize the patient and to perform preoperative staging, converting acute surgery into elective. SEMS is also proposed as palliative treatment in patients with contraindications to open surgery.

AIM

To review our experience of SEMS focusing on clinical outcome and complications. The method used was a review of 75 consecutive trials at SEMS on 71 patients based on stent-protocols and patient charts.

FINDINGS

SEMS was used for palliation in 64 (85%) cases and as a bridge to surgery in 11 (15%) cases. The majority of obstructions, 53 (71%) cases, were located in the recto-sigmoid. Technical success was achieved in 65 (87%) cases and clinical decompression was achieved in 60 (80%) cases. Reasons for technical failure were inability to cannulate the stricture in 5 (7%) cases and suboptimal SEMS placement in 3 (4%) cases. Complications included 4 (5%) procedure-related bowel perforations of which 2 (3%) patients died in junction to post operative complications. Three cases of bleeding after SEMS occurred, none of which needed invasive treatment. Five of the SEMS occluded. Two cases of stent erosion were diagnosed at the time of surgery. Average survival after palliative SEMS treatment was 6 months.

CONCLUSION

Our results correspond well to previously published data and we conclude that SEMS is a relatively safe and effective method of treating malignant colonic obstruction although the risk of SEMS-related perforations has to be taken into account.

摘要

背景

恶性结肠梗阻的急性手术治疗伴随着高发病率和死亡率。使用自膨式金属支架(SEMS)是一种结肠梗阻减压的替代方法。SEMS 可能使患者有时间进行优化并进行术前分期,将急性手术转变为择期手术。SEMS 也被提议用于有开放手术禁忌证患者的姑息治疗。

目的

回顾我们使用 SEMS 的经验,重点关注临床结果和并发症。所采用的方法是基于支架方案和患者病历对 71 例患者连续进行的 75 次 SEMS 试验进行回顾。

结果

SEMS 用于姑息治疗 64 例(85%),作为手术桥梁 11 例(15%)。大多数梗阻(53 例,71%)位于直肠乙状结肠。65 例(87%)技术成功,60 例(80%)实现临床减压。技术失败的原因包括 5 例(7%)无法通过狭窄部位插管,3 例(4%)SEMS 放置不理想。并发症包括 4 例(5%)与操作相关的肠穿孔,其中 2 例(3%)患者因术后并发症死亡。SEMS 术后发生 3 例出血,均无需侵入性治疗。5 例 SEMS 堵塞。手术时诊断出 2 例支架侵蚀。姑息性 SEMS 治疗后的平均生存期为 6 个月。

结论

我们的结果与先前发表的数据相符,我们得出结论,SEMS 是治疗恶性结肠梗阻的一种相对安全有效的方法,尽管必须考虑与 SEMS 相关的穿孔风险。

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