Baba M, Yamaguchi Y, Nomoto Y, Kohno H, Yamamoto N, Kakizawa K, Sekine Y, Takeda T, Shibuya K, Yamakawa K
Department of Surgery, Chiba University School of Medicine.
Kyobu Geka. 1992 Jan;45(1):45-50.
The advantages of laser irradiation were investigated retrospectively, using a total of 89 parenchyma-sparing pulmonary resection (PSPR) for localized lung lesions which included 42 conventional wedge resection (CWR), 8 PSPR using electrocoagulator (PE) and 39 PSPR using CO2 laser or Nd:YAG laser (PCYL). The major axes of the lesions in PNYL (25.4 +/- 10 mm) were significantly (p = 0.0387) longer than that in CWR (20.3 +/- 11.3 mm). The amount of bleeding during operation was similar in three groups. The mean value of the amount of postoperative exudation from the thoracic drains in PCYL (615 ml) was only 60 ml more than that in CWR. Bloody sputum was observed for 4.8 days in PCYL and 5.0 days in CWR, whereas 7.1 days in PE. Air leak was observed 33.3% in PCYL, 37.5% in PE, whereas 22.5% in CWR, that continued for 1.7 days (mean value) in PCYL, 1.6 days in PE and 2.0 days in CWR. Decrease (differences between preoperative and postoperative lung functions/volume of the lesions) in FVC and FEV1.0 in PCYL (mean values = 221, 158) and PE (174, 135) were less than that in CWR (339, 204). Laser assist in PSPR revealed advantages in hemostasis comparing with PE, and in parenchyma-sparing comparing with CWR. And no clear difference between PCYL and CWR in bleeding during operation, the amount of postoperative exudation and postoperative air leak. CO2 laser is reported that has higher potential in vaporization or cutting but lower ability in hemostasis comparing with Nd:YAG laser, so authors would express that Nd:YAG laser assist is most safe and effective in parenchyma-sparing lung resection.
回顾性研究了激光照射的优势,共对89例因局限性肺病变行肺实质保留切除术(PSPR)的患者进行分析,其中包括42例行传统楔形切除术(CWR)、8例行使用电凝器的PSPR(PE)以及39例行使用CO2激光或Nd:YAG激光的PSPR(PCYL)。PCYL组病变的长径(25.4±10mm)显著长于CWR组(20.3±11.3mm,p = 0.0387)。三组手术中的出血量相似。PCYL组术后胸腔引流管渗出量的平均值(615ml)仅比CWR组多60ml。PCYL组血性痰持续4.8天,CWR组为5.0天,而PE组为7.1天。PCYL组气漏发生率为33.3%,PE组为37.5%,CWR组为22.5%;PCYL组气漏持续时间(平均值)为1.7天,PE组为1.6天,CWR组为2.0天。PCYL组和PE组用力肺活量(FVC)和第1秒用力呼气容积(FEV1.0)的降低值(术前和术后肺功能/病变体积之差,平均值分别为221、158和174、135)小于CWR组(339、204)。与PE相比,激光辅助PSPR在止血方面具有优势,与CWR相比,在肺实质保留方面具有优势。并且PCYL组与CWR组在手术中的出血量、术后渗出量和术后气漏方面无明显差异。据报道,与Nd:YAG激光相比,CO2激光在汽化或切割方面具有更高的潜力,但止血能力较低,因此作者认为Nd:YAG激光辅助在肺实质保留肺切除术中最安全有效。