Bramlage Peter, Thoenes Martin, Kirch Wilhelm, Lenfant Claude
Institute for Clinical Pharmacology, Medical Faculty, Dresden, Germany.
Curr Med Res Opin. 2007 Apr;23(4):783-91. doi: 10.1185/030079907x182077.
High blood pressure (BP) is a leading risk factor for cardiovascular morbidity and mortality. Effective antihypertensive pharmacotherapy is available but recognition and proper management of hypertension and BP goal achievement is still poor. Therefore, it was hypothesized that physicians' attitude towards high BP, as well as patients' perception and knowledge, may influence actual management of hypertension.
Telephone interviews were carried out with a random sample of 1259 primary care physicians in 17 countries worldwide from 12 December 2005 to 13 January 2006 using a central computer assisted telephone interview methodology (CATI).
(1) Physicians believed that 62 +/- 21% of their patients had their BP controlled. (2) They were mostly in line with guideline recommended BP goals and 96% were aware of the elevated cardiovascular risk of hypertension, but 41% aimed to reduce BP to acceptable levels only. (3) Physicians indicated that in 41% of patients monotherapy controls BP and 71% would escalate to combination therapy after monotherapy failure. (4) 54% regard hypertension management as difficult. (5) Physicians estimated that between 60 and 70% of patients know their BP goal but thought that there was still room for improvement of hypertension management on the patient side.
Although many effective treatment options for arterial hypertension exist, BP goal achievement worldwide is suboptimal, leaving patients at an unnecessary cardiovascular risk. An increase in patients' awareness and compliance together with an increased adherence of physicians to current guidelines should help in reducing the long term cardiovascular consequences of hypertension.
高血压是心血管疾病发病和死亡的主要危险因素。有效的抗高血压药物治疗是可行的,但高血压的识别、恰当管理以及血压目标的达成情况仍不容乐观。因此,研究人员推测医生对高血压的态度以及患者的认知和知识水平可能会影响高血压的实际管理。
2005年12月12日至2006年1月13日,采用中央计算机辅助电话访谈方法(CATI),对全球17个国家的1259名初级保健医生进行随机抽样电话访谈。
(1)医生认为他们62±21%的患者血压得到了控制。(2)他们大多符合指南推荐的血压目标,96%的医生知晓高血压会增加心血管疾病风险,但41%的医生仅旨在将血压降至可接受水平。(3)医生指出,41%的患者单药治疗可控制血压,71%的医生会在单药治疗失败后升级为联合治疗。(4)54%的医生认为高血压管理困难。(5)医生估计60%至70%的患者知道自己的血压目标,但认为患者在高血压管理方面仍有改进空间。
尽管存在许多有效的动脉高血压治疗方案,但全球血压目标达成情况仍不理想,使患者面临不必要的心血管风险。提高患者的意识和依从性,以及医生对现行指南的更高依从性,应有助于减少高血压的长期心血管后果。