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较高的乳制品摄入量是否与较低的体重和较少的代谢紊乱有关?霍恩研究。

Is higher dairy consumption associated with lower body weight and fewer metabolic disturbances? The Hoorn Study.

作者信息

Snijder Marieke B, van der Heijden Amber Awa, van Dam Rob M, Stehouwer Coen D A, Hiddink Gerrit J, Nijpels Giel, Heine Robert J, Bouter Lex M, Dekker Jacqueline M

机构信息

Institute of Health Sciences, Faculty of Earth and Life Sciences, Vrije University, Amsterdam, Netherlands.

出版信息

Am J Clin Nutr. 2007 Apr;85(4):989-95. doi: 10.1093/ajcn/85.4.989.

Abstract

BACKGROUND

Dairy consumption has been postulated to reduce the risk of obesity and metabolic disturbances.

OBJECTIVE

The aim of this study was to evaluate the associations of dairy consumption with body weight and other components of the metabolic syndrome.

DESIGN

We used cross-sectional data for 2064 men and women aged 50-75 y who participated in the Hoorn Study. The metabolic syndrome was defined according to the National Cholesterol Education Program Expert Panel. Dairy consumption was assessed by using a semiquantitative food-frequency questionnaire.

RESULTS

The median consumption of total dairy products was 4.1 servings/d. After adjustment for potential confounders (ie, dietary factors, physical activity, smoking, income, educational level, and antihypertensive medication), total dairy consumption was significantly associated with lower diastolic blood pressure (beta +/- SE: -0.31 +/- 0.12 mm Hg/serving) and higher fasting glucose concentrations (0.04 +/- 0.02 mmol/L per serving), but not with body weight or other metabolic variables (ie, lipids, postload glucose, or insulin). When different dairy products were distinguished, borderline significant (P < 0.10) inverse associations were observed for dairy desserts, milk, and yogurt with systolic (-1.26 +/- 0.58, -0.57 +/- 0.34, and -1.28 +/- 0.74 mm Hg/serving, respectively) and diastolic (-0.58 +/- 0.31, -0.57 +/- 0.18, and -0.35 +/- 0.40 mm Hg/serving, respectively) blood pressure, whereas cheese consumption was positively associated with body mass index (0.15 +/- 0.08/serving).

CONCLUSION

In an elderly Dutch population, higher dairy consumption was not associated with lower weight or more favorable levels of components of the metabolic syndrome, except for a modest association with lower blood pressure.

摘要

背景

据推测,食用乳制品可降低肥胖和代谢紊乱的风险。

目的

本研究旨在评估乳制品消费与体重及代谢综合征其他组分之间的关联。

设计

我们使用了参与霍恩研究的2064名年龄在50 - 75岁的男性和女性的横断面数据。代谢综合征根据国家胆固醇教育计划专家小组的定义来确定。通过使用半定量食物频率问卷评估乳制品消费情况。

结果

总乳制品的中位消费量为4.1份/天。在对潜在混杂因素(即饮食因素、身体活动、吸烟、收入、教育水平和抗高血压药物)进行调整后,总乳制品消费与较低的舒张压(β±标准误:-0.31±0.12 mmHg/份)和较高的空腹血糖浓度(0.04±0.02 mmol/L/份)显著相关,但与体重或其他代谢变量(即血脂、负荷后血糖或胰岛素)无关。当区分不同的乳制品时,观察到乳制品甜点、牛奶和酸奶与收缩压(分别为-1.26±0.58、-0.57±0.34和-1.28±0.74 mmHg/份)和舒张压(分别为-0.58±0.31、-0.57±0.18和-0.35±0.40 mmHg/份)呈边缘显著(P<0.10)的负相关,而食用奶酪与体重指数呈正相关(0.15±0.08/份)。

结论

在荷兰老年人群中,较高的乳制品消费与较低体重或更有利的代谢综合征组分水平无关,仅与较低血压有适度关联。

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